Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

618 questions · 646 findings · 79 reviews · Neonatal

No studies found 73 · 11.3%GRADE not reported 29 · 4.5%Very low 145 · 22.4%Low 177 · 27.4%Moderate 173 · 26.8%High 49 · 7.6%

High vs standard volume of unfortified human milk or term formula

Necrotising enterocolitis · preterm or low birth weight infants

It is very uncertain whether high changes necrotising enterocolitis compared with standard volume of unfortified human milk or term formula (very low certainty).

1 finding from 1 review

High vs standard volume of fortified human milk or preterm formula

Extrauterine growth restriction at discharge · preterm or low birth weight infants

High showed no clear difference in extrauterine growth restriction at discharge compared with standard volume of fortified human milk or preterm formula (low certainty).

1 finding from 1 review

High vs standard volume of fortified human milk or preterm formula

Necrotising enterocolitis · preterm or low birth weight infants

It is very uncertain whether high changes necrotising enterocolitis compared with standard volume of fortified human milk or preterm formula (very low certainty).

1 finding from 1 review