Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

309 questions · 330 findings · 31 reviews

No studies found 59 · 17.9%GRADE not reported 63 · 19.1%Very low 93 · 28.2%Low 77 · 23.3%Moderate 27 · 8.2%High 11 · 3.3%

Probiotics vs placebo

Relief of pain · Children with recurrent abdominal pain

Probiotics probably leads to higher improvement in pain: 0 to 3 months' postintervention Different… compared with placebo (moderate certainty).

2 findings from 1 review

Probiotics vs placebo

Improvement in pain: 0 to 3 months' postintervention Subgroup (irritable bowel syndrome) Different measures were used to assess improvement in pain, as above. · Children with recurrent abdominal pain

Probiotics probably leads to higher improvement in pain: 0 to 3 months' postintervention Subgroup… compared with placebo (moderate certainty).

1 finding from 1 review

Fibre vs placebo

Improvement in pain: 0 to 3 months' postintervention Improvement in pain was defined and measured differently in the 2 included studies: using a "stomach ache diary" and the Faces Pain Scale (Bieri 1990). · Children with recurrent abdominal pain

Fibre showed no clear difference in improvement in pain: 0 to 3 months' postintervention Improvement in… compared with placebo (low certainty).

1 finding from 1 review

Potassium citrate vs no intervention

Proportion of participants who developed a new urinary stone · children with idiopathic urinary calculi treated with shockwave lithotripsy

Potassium citrate may leads to lower proportion of participants who developed a new urinary stone compared with no intervention (low certainty).

1 finding from 1 review

Potassium citrate vs no intervention

Proportion of participants with adverse events while undergoing intervention · children with idiopathic urinary calculi treated with shockwave lithotripsy

It is very uncertain whether potassium citrate changes proportion of participants with adverse events while undergoing… compared with no intervention (very low certainty).

1 finding from 1 review