Question · asked by 1 review

Probiotics vs placebo: Relief of pain

Probiotics probably leads to higher improvement in pain: 0 to 3 months' postintervention Different… compared with placebo (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Probiotics vs placebo
Improvement in pain: 0 to 3 months' postintervention Different measures and definitions were used for improvement in pain, such as Likert scale, visual analogue scale, and Subject’s Global Assessment of Relief Scale (McGrath 1996; Muller‐Lissner 2... · Children with recurrent abdominal pain
Probiotics probably leads to higher improvement in pain: 0 to 3 months' postintervention Different… compared with placebo (moderate certainty).
Dietary interventions for recurrent abdominal pain in childhood (2017) · Cochrane Headline outcomes only
OR 1.63 [1.07, 2.47]7 studies · 722 participantsModerate
Probiotics vs placebo
Improvement in pain: 3 to 6 months' postintervention Different measures were used to assess improvement in pain, as above. · Children with recurrent abdominal pain
Probiotics probably leads to higher improvement in pain: 3 to 6 months' postintervention Different… compared with placebo (moderate certainty).
Dietary interventions for recurrent abdominal pain in childhood (2017) · Cochrane Headline outcomes only
OR 1.94 [1.1, 3.43]2 studies · 224 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Dietary interventions for recurrent abdominal pain in childhood
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.