Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,584 questions · 3,695 findings · 567 reviews

No studies found 784 · 21.2%GRADE not reported 308 · 8.3%Very low 1,036 · 28%Low 971 · 26.3%Moderate 440 · 11.9%High 156 · 4.2%

SDAC + hospital intervention vs hospital intervention

Incidence of mortality · first aid in patients with acute oral poisoning (not specified, tricyclic antidepressants, combinations of different drugs or yellow…

SDAC + hospital intervention showed no clear difference in incidence of mortality compared with hospital intervention alone (low certainty).

1 finding from 1 review

Self-etch adhesive + acetone-based total-etch adhesive vs Total-etching 36% phosphoric acid + acetone-based total-etch adhesive

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes radiological failure compared with total-etching 36% phosphoric acid + acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

Selective vs routine episiotomy: all vaginal births where operative vaginal delivery was not anticipated

Severe perineal/vaginal trauma · Women in labour where operative delivery was not anticipated. (Women were above 16 years old and between 28 gestational weeks and full…

Selective may leads to lower severe perineal/vaginal trauma compared with routine episiotomy: all vaginal births where operative vaginal… (low certainty).

1 finding from 1 review

Selective vs routine episiotomy: all vaginal births where operative vaginal delivery was not anticipated

Perineal infection · Women in labour where operative delivery was not anticipated. (Women were above 16 years old and between 28 gestational weeks and full…

Selective showed no clear difference in perineal infection compared with routine episiotomy: all vaginal births where operative vaginal… (low certainty).

1 finding from 1 review

Selective vs routine episiotomy: all vaginal births where operative vaginal delivery was not anticipated

Women with moderate or severe pain (measured by visual analogue scale) · Women in labour where operative delivery was not anticipated. (Women were above 16 years old and between 28 gestational weeks and full…

It is very uncertain whether selective changes women with moderate or severe pain (measured by visual analogue scale) compared with routine episiotomy: all vaginal births where operative vaginal… (very low certainty).

1 finding from 1 review

Selective vs routine episiotomy: all vaginal births where operative vaginal delivery was not anticipated

Women with long‐term dyspareunia (≥ 6 months) · Women in labour where operative delivery was not anticipated. (Women were above 16 years old and between 28 gestational weeks and full…

Selective showed no clear difference in women with long‐term dyspareunia (≥ 6 months) compared with routine episiotomy: all vaginal births where operative vaginal… (moderate certainty).

1 finding from 1 review

Selective vs routine episiotomy: all vaginal births where operative vaginal delivery was not anticipated

Women with long‐term urinary incontinence (≥ 6 months) · Women in labour where operative delivery was not anticipated. (Women were above 16 years old and between 28 gestational weeks and full…

Selective showed no clear difference in women with long‐term urinary incontinence (≥ 6 months) compared with routine episiotomy: all vaginal births where operative vaginal… (low certainty).

1 finding from 1 review

Primary outcome: topical local anaesthetics vs infiltrated local anaesthetics or other topical agents

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults and paediatric patients with dermal laceration
5 findings from 1 review
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Primary outcome: topical local anaesthetics vs infiltrated local anaesthetics or other topical agents

Anaesthetic‐related adverse effects · adults and paediatric patients with dermal laceration

Primary outcome: topical local anaesthetics led to lower anaesthetic‐related adverse effects compared with infiltrated local anaesthetics or other topical agents; GRADE not reported.

1 finding from 1 review

Intervention not reported

All‐cause mortality Median · adults older than 18 years, with no restriction regarding presence of ASCVD; participants generally had elevated risk of ASCVD (as…

The intervention showed no clear difference in all‐cause mortality Median (low certainty).

1 finding from 1 review