Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

4,756 questions · 13,493 findings · 1,305 reviews · Headline outcomes only

No studies found 2,594 · 19.2%GRADE not reported 728 · 5.4%Very low 2,868 · 21.3%Low 3,777 · 28%Moderate 2,620 · 19.4%High 906 · 6.7%

Ranked among the 5,000 newest matching findings; add words or filters to narrow the search.

Probiotics vs placebo

Global improvement or treatment success, as defined by primary study · children with chronic constipation without a physical explanation

Probiotic may leads to higher global improvement/treatment success as defined by primary study compared with placebo (low certainty).

1 finding from 1 review

Probiotics vs placebo

Withdrawals due to adverse events · children with chronic constipation without a physical explanation

Probiotic showed no clear difference in withdrawals due to adverse events compared with placebo (low certainty).

1 finding from 1 review

Dexrazoxane vs no cardioprotective intervention or placebo

Heart failure · adults with cancer receiving anthracyclines

Dexrazoxane probably leads to lower clinical heart failure Available case analysis compared with no cardioprotective intervention or placebo (moderate certainty).

1 finding from 1 review

Dexrazoxane vs no cardioprotective intervention or placebo

Clinical heart failure and subclinical myocardial dysfunction combined Comparable definitions; see Characteristics of included studies for exact definitions. Available‐case analysis · adults with cancer receiving anthracyclines

Dexrazoxane probably leads to lower clinical heart failure and subclinical myocardial dysfunction… compared with no cardioprotective intervention or placebo (moderate certainty).

2 findings from 1 review

Dexrazoxane vs no cardioprotective intervention or placebo

Overall survival (Illustrative comparative risks reported as number of alive participants) · adults with cancer receiving anthracyclines

Dexrazoxane showed no clear difference in overall survival (Illustrative comparative risks reported as number… compared with no cardioprotective intervention or placebo (moderate certainty).

1 finding from 1 review

Dexrazoxane vs no cardioprotective intervention or placebo

Progression‐free survival · adults with cancer receiving anthracyclines

Dexrazoxane may leads to lower progression‐free survival Defined as time from first date of… compared with no cardioprotective intervention or placebo (low certainty).

3 findings from 1 review

Dexrazoxane vs no cardioprotective intervention or placebo

Partial response (partial or complete response) · adults with cancer receiving anthracyclines

Dexrazoxane showed no clear difference in tumour response rate Defined as number of complete or partial… compared with no cardioprotective intervention or placebo (moderate certainty).

1 finding from 1 review