Oral mucositis (any severity) · Adults with cancer receiving treatment
Granulocyte-macrophage colony-stimulating factor (GM-CSF) showed no clear difference in oral mucositis (any severity) compared with placebo or no treatment; GRADE not reported.
2 findings from 1 review
Salivary flow rate (stimulated) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
Chinese medicine led to higher salivary flow rate (stimulated) compared with no treatment/placebo; GRADE not reported.
1 finding from 1 review
Participant experience (dental anxiety) · Children with carious primary teeth
ART using composite resin showed no clear difference in participant experience (dental anxiety) compared with conventional treatment using composite resin; GRADE not reported.
1 finding from 1 review
Xerostomia (grade >= 2, 0-4 scale) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
Palifermin showed no clear difference in xerostomia (grade >= 2, 0-4 scale) compared with placebo (low certainty).
1 finding from 1 review
Bridge failure · Adults (18 years or older) needing a three-unit fixed dental prosthesis (FDP)
1 finding from 1 review
Adverse events (illness, allergy, bad taste, mucosal trauma) · Participants with full arch fixed orthodontic appliance(s) with molar tubes bonded to first or second permanent molars; excludes prior…
1 finding from 1 review
Time off school or work · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
The review found no eligible studies for this question.
1 finding from 1 review
Marginal bone level change · Adults (18 years or older) with one missing tooth in the aesthetic zone needing an implant-supported single crown
Metal-free implant abutments (zirconia) showed no clear difference in marginal bone level change (MBLC) compared with metal implant abutments (titanium); GRADE not reported.
2 findings from 1 review
Bridge complications · Adults (18 years or older) needing an implant-supported fixed dental prosthesis in the posterior region
It is very uncertain whether metal-free implant-supported FDPs (zirconia-toughened alumina;… changes bridge complications compared with metal-free implant-supported FDPs (yttria-stabilized tetragonal… (very low certainty).
4 findings from 1 review
OR 0.02 [0.00, 0.42]
1 study · 18 participants
Very low
OR 0.02 [0.00, 0.30]
1 study · 18 participants
Very low
OR 0.04 [0.00, 0.48]
1 study · 18 participants
Very low
Show 1 more finding
Gestational age (preterm birth < 37 weeks) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
Periodontal treatment (scaling and root planing, polishing, or… showed no clear difference in gestational age (preterm birth < 37 weeks) compared with no treatment (low certainty).
1 finding from 1 review
Drooling (hyposialosis) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
Antiseptic mouthrinse showed no clear difference in drooling (hyposialosis) compared with placebo; GRADE not reported.
1 finding from 1 review
Taste discrimination improvement · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
1 finding from 1 review
Number of days in hospital · Adults with cancer receiving treatment
Keratinocyte growth factor (KGF; palifermin or repifermin),… showed no clear difference in number of days in hospital compared with placebo; GRADE not reported.
1 finding from 1 review
Low birth weight (< 2.5 kg) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
It is very uncertain whether periodontal treatment (scaling and root planing, alone or with… changes low birth weight < 2500 g compared with alternative (less intensive) periodontal treatment, alone or with… (very low certainty).
1 finding from 1 review
Oral mucositis (severe) · Adults with cancer receiving treatment
Granulocyte-macrophage colony-stimulating factor (GM-CSF) showed no clear difference in oral mucositis (severe) compared with placebo or no treatment (low certainty).
3 findings from 1 review
RR 0.74 [0.33, 1.67]
3 studies · 235 participants
Low
RR 0.59 [0.05, 7.11]
2 studies · 65 participants
Very low
RR 0.31 [0.01, 7.09]
1 study · 29 participants
Very low
Quality of life (McMaster HNRQ, 1-7 scale) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
It is very uncertain whether pilocarpine changes quality of life (McMaster HNRQ, 1-7 scale) compared with no treatment/placebo (very low certainty).
1 finding from 1 review
Clinical stability of osteotomy segments (VAS 0 to 10) · Adults (>16 years old) undergoing orthognathic surgery
1 finding from 1 review
Clinical stability of osteotomy segments (Cheung 2004), self-assessed on a VAS (0=very mobile, 10=no mobility) by postoperative period, titanium vs resorbable mean (SD): 0 to 2 weeks 8.10 (1.79) vs 8.47 (2.18), P=0.48;…
1 study · 60 participants
GRADE not reported
Adverse effects (apart from fluorosis) · Pregnant women (for preventing dental caries in the primary teeth of their children)
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Restoration failure (primary dentition) · Children with carious primary teeth
ART using H-GIC showed no clear difference in restoration failure (primary teeth) compared with conventional treatment using amalgam; GRADE not reported.
1 finding from 1 review
OR 2.15 [0.73, 6.35]
2 studies
GRADE not reported
Plaque · Adults (18 years or older) needing replacement of one premolar or incisor with a cantilevered fixed dental prosthesis
Metal-free cantilevered FDPs (feldspathic-veneered zirconia) showed no clear difference in plaque index (PI) compared with metal-ceramic cantilevered FDPs; GRADE not reported.
1 finding from 1 review