Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Non‐healthcare professional‐led breastfeeding education and support vs usual care

Early initiation of breastfeeding · women exposed to interventions intended to promote breastfeeding

It is very uncertain whether non‐healthcare professional‐led breastfeeding education and support changes early initiation of breastfeeding compared with standard care (very low certainty).

1 finding from 1 review

Intervention not reported

Breastfeeding 1 month to 4 months post birth · mothers and their healthy newborn infants

The intervention probably leads to higher breastfeeding 1 month to 4 months post birth (moderate certainty).

1 finding from 1 review

Intervention not reported

Exclusive breastfeeding at hospital discharge to 1 month post birth · mothers and their healthy newborn infants

The intervention probably leads to higher exclusive breastfeeding at hospital discharge to 1 month post birth (moderate certainty).

1 finding from 1 review

Intervention not reported

Exclusive breastfeeding 6 weeks to 6 months post birth · mothers and their healthy newborn infants

The intervention probably leads to higher exclusive breastfeeding 6 weeks to 6 months post birth (moderate certainty).

1 finding from 1 review

Vitamin E + vitamin C vs placebo

Any adverse effects of vitamin supplementation sufficient to stop supplementation · pregnant women

Vitamin C and vitamin E showed no clear difference in any adverse effects of vitamin supplementation sufficient to stop… compared with placebo (moderate certainty).

1 finding from 1 review

Multivitamin plus iron plus folate vs iron plus folate

Total fetal loss (including miscarriages or combined miscarriages and stillbirths) · pregnant women

Multivitamin plus iron plus folate showed no clear difference in total fetal loss (including miscarriages or combined miscarriages… compared with iron plus folate (high certainty).

1 finding from 1 review