Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,345 questions · 4,525 findings · 483 reviews

No studies found 1,024 · 22.6%GRADE not reported 388 · 8.6%Very low 1,172 · 25.9%Low 1,227 · 27.1%Moderate 576 · 12.7%High 138 · 3%

Dialkylcarbamoyl chloride (DACC)‐coated dressing vs alginate dressing

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

The review found no eligible studies for this question.

1 finding from 1 review

Dialkylcarbamoyl chloride (DACC)‐coated dressing vs alginate dressing

Adverse effects (surgical site infection or allergic reaction) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

The review found no eligible studies for this question.

1 finding from 1 review

Negative pressure wound therapy vs conventional open wound healing

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

The review found no eligible studies for this question.

1 finding from 1 review

Suprasorb CNP system vs the ABThera system

Proportion of participants with successful primary fascial closure of the abdomen · adults with an open abdomen after surgery who have not experienced trauma

It is very uncertain whether suprasorb CNP system changes proportion of participants with successful primary fascial closure… compared with the ABThera system (very low certainty).

1 finding from 1 review

Suprasorb CNP system vs the ABThera system

Adverse events (fistulae formation) · adults with an open abdomen after surgery who have not experienced trauma

It is very uncertain whether suprasorb CNP system changes adverse events (fistulae formation) compared with the ABThera system (very low certainty).

1 finding from 1 review

Super ethoxybenzoic acid (Super-EBA) vs Intermediate restorative material (IRM)

Success rate at 1 year · Patients needing retrograde filling in root canal therapy (orthograde root canal filling or retreatment not possible; periapical surgery…

It is very uncertain whether super ethoxybenzoic acid (Super-EBA) changes success rate at 1 year compared with intermediate restorative material (IRM) (very low certainty).

1 finding from 1 review

Dentine-bonded resin composite vs Glass ionomer cement (GIC)

Success rate at 1 year · Patients needing retrograde filling in root canal therapy (orthograde root canal filling or retreatment not possible; periapical surgery…

It is very uncertain whether dentine-bonded resin composite changes success rate at 1 year (root as unit, per-protocol analysis) compared with glass ionomer cement (very low certainty).

2 findings from 1 review