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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
2,653 questions in 194 reviews · Gynaecology and Fertility
current versionsNo studies 531 · 20%Ungraded 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pentoxifylline vs placebo Clinical pregnancy rate · women with endometriosis Pentoxifylline for the treatment of endometriosis‐associated pain and infertility (2021) · Cochrane | RR 1.38 [0.91, 2.1] | 3 studies · 285 participants | Very low |
Pentoxifylline vs placebo Miscarriage rate · women with endometriosis Pentoxifylline for the treatment of endometriosis‐associated pain and infertility (2021) · Cochrane | Peto OR 1.99 [0.2, 19.37] | 2 studies · 164 participants | Very low |
Pentoxifylline vs placebo Recurrence rate of endometriosis · women with endometriosis Pentoxifylline for the treatment of endometriosis‐associated pain and infertility (2021) · Cochrane | RR 0.84 [0.3, 2.36] | 1 study · 121 participants | Very low |
Pentoxifylline vs placebo Adverse events · women with endometriosis Pentoxifylline for the treatment of endometriosis‐associated pain and infertility (2021) · Cochrane | no estimate extracted | NR | No studies |
Pentoxifylline vs no treatment Live birth rate · women with endometriosis Pentoxifylline for the treatment of endometriosis‐associated pain and infertility (2021) · Cochrane | no estimate extracted | NR | No studies |
Pentoxifylline vs no treatment Overall pain ‐ 1 month · women with endometriosis Pentoxifylline for the treatment of endometriosis‐associated pain and infertility (2021) · Cochrane | no estimate extracted | 1 study · 34 participants | Very low |
Pentoxifylline vs no treatment Overall pain ‐ 2 months · women with endometriosis Pentoxifylline for the treatment of endometriosis‐associated pain and infertility (2021) · Cochrane | no estimate extracted | 1 study · 34 participants | Very low |
Preconception lifestyle advice on a combination of topics vs routine care or attention control Live birth · people with infertility Preconception lifestyle advice for people with infertility (2021) · Cochrane | RR 0.93 [0.79, 1.1] | 1 study · 626 participants | Low |
Preconception lifestyle advice on weight vs routine care or attention control Adverse events ‐ Hypertension · women with infertility and obesity Preconception lifestyle advice for people with infertility (2021) · Cochrane | RR 1.07 [0.66, 1.75] | 1 study · 317 participants | Very low |
Preconception lifestyle advice on weight vs routine care or attention control Adverse events ‐ Gestational diabetes · women with infertility and obesity Preconception lifestyle advice for people with infertility (2021) · Cochrane | RR 0.78 [0.48, 1.26] | 1 study · 317 participants | Very low |
Preconception lifestyle advice on weight vs routine care or attention control Miscarriage · women with infertility and obesity Preconception lifestyle advice for people with infertility (2021) · Cochrane | RR 1.5 [0.95, 2.37] | 1 study · 577 participants | Very low |
Preconception lifestyle advice on weight vs routine care or attention control Reported behavioural changes in weight: BMI (measured at 6 months) · women with infertility and obesity Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | 1 study · 574 participants | Low |
Preconception lifestyle advice on weight vs routine care or attention control Reported behavioural changes in weight: percentage of weight loss (measured at 6 months) · women with infertility and obesity Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | 2 studies · 380 participants | Very low |
Preconception lifestyle advice on weight vs routine care or attention control Reported behavioural changes in diet: vegetable intake · women with infertility and obesity Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | 1 study · 250 participants | Very low |
Preconception lifestyle advice on weight vs routine care or attention control Reported behavioural changes in diet: fruit intake · women with infertility and obesity Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | 1 study · 258 participants | Very low |
Preconception lifestyle advice on weight vs routine care or attention control Reported behavioural changes in alcohol intake · women with infertility and obesity Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | 1 study · 239 participants | Very low |
Preconception lifestyle advice on weight vs routine care or attention control Reported behavioural changes in physical activity · women with infertility and obesity Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | 1 study · 254 participants | Very low |
Preconception lifestyle advice on alcohol intake vs routine care or attention control Live birth · women with infertility and at‐risk drinking Preconception lifestyle advice for people with infertility (2021) · Cochrane | RR 1.15 [0.53, 2.5] | 1 study · 37 participants | Very low |
Preconception lifestyle advice on a combination of topics vs routine care or attention control Adverse events · people with infertility Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | NR | No studies |
Preconception lifestyle advice on alcohol intake vs routine care or attention control Adverse events · women with infertility and at‐risk drinking Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | NR | No studies |
Preconception lifestyle advice on alcohol intake vs routine care or attention control Miscarriage · women with infertility and at‐risk drinking Preconception lifestyle advice for people with infertility (2021) · Cochrane | RR 1.31 [0.21, 8.34] | 1 study · 37 participants | Very low |
Preconception lifestyle advice on alcohol intake vs routine care or attention control Reported behavioural changes · women with infertility and at‐risk drinking Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | NR | No studies |
Preconception lifestyle advice on smoking vs routine care or attention control Live birth or ongoing pregnancy · smoking people with infertility Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | NR | No studies |
Preconception lifestyle advice on smoking vs routine care or attention control Adverse events · smoking people with infertility Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | NR | No studies |
Preconception lifestyle advice on smoking vs routine care or attention control Miscarriage · smoking people with infertility Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | NR | No studies |
Preconception lifestyle advice on smoking vs routine care or attention control Reported behavioural changes: smoking · smoking people with infertility Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | NR | No studies |
Preconception lifestyle advice on a combination of topics vs routine care or attention control Miscarriage · people with infertility Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | NR | No studies |
Preconception lifestyle advice on a combination of topics vs routine care or attention control Reported behavioural changes in weight: BMI (measured "at study end" ‐ 3 months) · people with infertility Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | 1 study · 180 participants | Very low |
Preconception lifestyle advice on a combination of topics vs routine care or attention control Reported behavioural changes in diet: vegetable intake · people with infertility Preconception lifestyle advice for people with infertility (2021) · Cochrane | no estimate extracted | 1 study · 264 participants | Very low |
Preconception lifestyle advice on a combination of topics vs routine care or attention control Reported behavioural changes on vitamin or mineral supplement intake: number of women with adequate use of folic acid supplement · people with infertility Preconception lifestyle advice for people with infertility (2021) · Cochrane | RR 0.98 [0.95, 1.01] | 2 studies · 850 participants | Low |
Preconception lifestyle advice on a combination of topics vs routine care or attention control Reported behavioural changes in alcohol intake (measured at 6 months) · people with infertility Preconception lifestyle advice for people with infertility (2021) · Cochrane | RR 1.07 [0.99, 1.17] | 1 study · 607 participants | Low |
Preconception lifestyle advice on a combination of topics vs routine care or attention control Reported behavioural changes in smoking (measured at 6 months): · people with infertility Preconception lifestyle advice for people with infertility (2021) · Cochrane | RR 1.01 [0.98, 1.04] | 1 study · 606 participants | Low |
Preconception lifestyle advice on weight vs routine care or attention control Live birth · women with infertility and obesity Preconception lifestyle advice for people with infertility (2021) · Cochrane | RR 0.94 [0.62, 1.43] | 2 studies · 707 participants | Very low |
Summary of findings table ‐ Adhesiolysis vs no surgery or diagnostic laparoscopy Effectiveness of treatment · health problem or population Surgical interventions for the management of chronic pelvic pain in women (2021) · Cochrane | no estimate extracted | 1 study · 43 participants | Low |
Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments Effectiveness of treatment · health problem or population Surgical interventions for the management of chronic pelvic pain in women (2021) · Cochrane | no estimate extracted | 1 study · 74 participants | Very low |
Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments Effectiveness of treatment · health problem or population Surgical interventions for the management of chronic pelvic pain in women (2021) · Cochrane | no estimate extracted | 1 study · 74 participants | Very low |
Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments Adverse events · health problem or population Surgical interventions for the management of chronic pelvic pain in women (2021) · Cochrane | no estimate extracted | 2 studies · 121 participants | Ungraded |
Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments Psychological outcomes ‐ not reported · health problem or population Surgical interventions for the management of chronic pelvic pain in women (2021) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments Quality of life ‐ not reported · health problem or population Surgical interventions for the management of chronic pelvic pain in women (2021) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments Requirement for analgesia · health problem or population Surgical interventions for the management of chronic pelvic pain in women (2021) · Cochrane | no estimate extracted | 1 study · 74 participants | Ungraded |
Summary of findings table ‐ Adhesiolysis vs no surgery or diagnostic laparoscopy Effectiveness of treatment · health problem or population Surgical interventions for the management of chronic pelvic pain in women (2021) · Cochrane | no estimate extracted | 1 study · 43 participants | Low |
Summary of findings table ‐ Adhesiolysis vs no surgery or diagnostic laparoscopy Effectiveness of treatment · health problem or population Surgical interventions for the management of chronic pelvic pain in women (2021) · Cochrane | no estimate extracted | 1 study · 43 participants | Very low |
Summary of findings table ‐ Adhesiolysis vs no surgery or diagnostic laparoscopy Adverse events · health problem or population Surgical interventions for the management of chronic pelvic pain in women (2021) · Cochrane | no estimate extracted | 1 study · 43 participants | Low |
Summary of findings table ‐ Adhesiolysis vs no surgery or diagnostic laparoscopy Psychological outcomes ‐ not reported · health problem or population Surgical interventions for the management of chronic pelvic pain in women (2021) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Adhesiolysis vs no surgery or diagnostic laparoscopy Quality of life · health problem or population Surgical interventions for the management of chronic pelvic pain in women (2021) · Cochrane | no estimate extracted | 1 study · 43 participants | Low |
Summary of findings table ‐ Adhesiolysis vs no surgery or diagnostic laparoscopy Quality of life · health problem or population Surgical interventions for the management of chronic pelvic pain in women (2021) · Cochrane | no estimate extracted | 1 study · 43 participants | Low |
Summary of findings table ‐ Adhesiolysis vs no surgery or diagnostic laparoscopy Requirement for analgesia ‐ not reported · health problem or population Surgical interventions for the management of chronic pelvic pain in women (2021) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments Effectiveness of treatment · health problem or population Surgical interventions for the management of chronic pelvic pain in women (2021) · Cochrane | OR 1.26 [0.4, 3.93] | 1 study · 51 participants | Low |
Dopamine agonist vs placebo/no intervention Incidence of moderate or severe OHSS · women of reproductive age undergoing any ART therapy Dopamine agonists for preventing ovarian hyperstimulation syndrome (2021) · Cochrane | OR 0.32 [0.23, 0.44] | 10 studies · 1202 participants | Moderate |
Dopamine agonist plus co‐intervention vs co‐intervention Multiple pregnancy rate · women of reproductive age undergoing any ART therapy Dopamine agonists for preventing ovarian hyperstimulation syndrome (2021) · Cochrane | OR 2.02 [0.18, 22.77] | 1 study · 166 participants | Very low |