Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

2,325 questions in 216 reviews · Airways

current versions
No studies 249 · 10.7%Ungraded 107 · 4.6%Very low 276 · 11.9%Low 751 · 32.3%Moderate 718 · 30.9%High 224 · 9.6%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Remote monitoring vs usual care
Number of people experiencing 1 or more exacerbations · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
OR 1.02 [0.67, 1.55]4 studies · 424 participantsVery low
Remote monitoring vs usual care
Quality of life · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Remote monitoring vs usual care
SGRQ total score · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extracted1 study · 45 participantsVery low
Remote monitoring vs usual care
CAT score · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extracted2 studies · 405 participantsVery low
Remote monitoring vs usual care
CAT total score · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extracted1 study · 229 participantsVery low
Remote monitoring vs usual care
Symptoms of dyspnoea · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Remote monitoring vs usual care
CRQ‐SAS dyspnoea symptoms score · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extracted1 study · 70 participantsLow
Remote monitoring plus usual care vs usual care
Number of people experiencing 1 or more exacerbations · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
OR 1.25 [0.59, 2.67]1 study · 108 participantsVery low
Remote monitoring vs usual care
Number of people admitted to hospital · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
OR 1.21 [0.75, 1.94]2 studies · 357 participantsVery low
Remote monitoring vs usual care
Mortality · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Remote monitoring vs usual care
Mortality (all‐cause) · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
OR 0.68 [0.37, 1.25]6 studies · 798 participantsVery low
Multi‐component interventions (with telehealth as a component of care) vs usual care
Exacerbations · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Multi‐component interventions (with telehealth as a component of care) vs usual care
Number of people experiencing at least 1 exacerbation/moderate to severe exacerbation · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
OR 0.98 [0.74, 1.28]3 studies · 955 participantsVery low
Multi‐component interventions (with telehealth as a component of care) vs usual care
Time to first exacerbation · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
HR 1.05 [0.67, 1.65]1 study · 166 participantsVery low
Multi‐component interventions (with telehealth as a component of care) vs usual care
Quality of life · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Multi‐component interventions (with telehealth as a component of care) vs usual care
SGRQ total score · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extracted1 study · 38 participantsLow
Multi‐component interventions (with telehealth as a component of care) vs usual care
SGRQ total score · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extracted1 study · 40 participantsVery low
Multi‐component interventions (with telehealth as a component of care) vs usual care
SGRQ total score · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extracted2 studies · 203 participantsVery low
Remote monitoring plus usual care vs usual care
Quality of life · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Multi‐component interventions (with telehealth as a component of care) vs usual care
CAT score · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extracted2 studies · 521 participantsVery low
Multi‐component interventions (with telehealth as a component of care) vs usual care
Dyspnoea symptoms · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Multi‐component interventions (with telehealth as a component of care) vs usual care
No evidence identified · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Multi‐component interventions (with telehealth as a component of care) vs usual care
Number of people who had at least 1 hospital admission · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
OR 0.81 [0.55, 1.18]2 studies · 447 participantsLow
Multi‐component interventions (with telehealth as a component of care) vs usual care
Number of people re‐admitted (all‐cause) · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
OR 0.5 [0.31, 0.81]3 studies · 344 participantsModerate
Multi‐component interventions (with telehealth as a component of care) vs usual care
Mortality · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Multi‐component interventions (with telehealth as a component of care) vs usual care
Mortality (all‐cause) overall analysis · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
OR 0.62 [0.39, 1.01]9 studies · 1886 participantsVery low
Multi‐component interventions (with telehealth as a component of care) vs usual care
Adverse events: number of people with 1 or more (all‐cause) · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
OR 0.91 [0.62, 1.33]2 studies · 485 participantsVery low
Remote monitoring plus usual care vs usual care
SGRQ total score · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extracted2 studies · 204 participantsVery low
Remote monitoring plus usual care vs usual care
SGRQ total score · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extracted1 study · 205 participantsVery low
Remote monitoring plus usual care vs usual care
Dyspnoea symptoms · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Remote monitoring plus usual care vs usual care
No evidence identified · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Remote monitoring plus usual care vs usual care
Time to first hospitalisation after starting intervention · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
HR 1.08 [0.8, 1.46]1 study · 256 participantsVery low
Remote monitoring plus usual care vs usual care
Time to first COPD‐related re‐admission · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
HR 0.42 [0.19, 0.93]1 study · 106 participantsModerate
Digital intervention with or without routine supported self‐management vs control
Impact on health behaviour: 6MWD · the management of chronic obstructive pulmonary disease
Digital interventions for the management of chronic obstructive pulmonary disease (2021) · Cochrane
no estimate extracted2 studies · 122 participantsVery low
Multi‐component intervention vs other intervention or routine, usual care or control treatment
Adverse events: number of people experiencing an AE · the management of chronic obstructive pulmonary disease
Digital interventions for the management of chronic obstructive pulmonary disease (2021) · Cochrane
OR 1.07 [0.51, 2.25]1 study · 166 participantsVery low
Multi‐component intervention vs other intervention or routine, usual care or control treatment
Adverse events: number of people experiencing a serious adverse event · the management of chronic obstructive pulmonary disease
Digital interventions for the management of chronic obstructive pulmonary disease (2021) · Cochrane
OR 0.85 [0.55, 1.34]1 study · 319 participantsLow
Digital intervention with or without routine supported self‐management vs control
Self‐efficacy: PRAISE · the management of chronic obstructive pulmonary disease
Digital interventions for the management of chronic obstructive pulmonary disease (2021) · Cochrane
no estimate extracted1 study · 55 participantsVery low
Digital intervention with or without routine supported self‐management vs control
Self‐efficacy: SEMCD total · the management of chronic obstructive pulmonary disease
Digital interventions for the management of chronic obstructive pulmonary disease (2021) · Cochrane
no estimate extracted1 study · 42 participantsVery low
Digital intervention with or without routine supported self‐management vs control
Quality of life: CRQ total, SGRQ total or CAT · the management of chronic obstructive pulmonary disease
Digital interventions for the management of chronic obstructive pulmonary disease (2021) · Cochrane
no estimate extracted2 studies · 123 participantsLow
Digital intervention with or without routine supported self‐management vs control
Dyspnoea symptoms: CRQ dyspnoea · the management of chronic obstructive pulmonary disease
Digital interventions for the management of chronic obstructive pulmonary disease (2021) · Cochrane
no estimate extracted1 study · 84 participantsLow
Digital intervention with or without routine supported self‐management vs control
Exacerbations: mean number of exacerbations · the management of chronic obstructive pulmonary disease
Digital interventions for the management of chronic obstructive pulmonary disease (2021) · Cochrane
no estimate extracted1 study · 69 participantsLow
Multi‐component intervention vs other intervention or routine, usual care or control treatment
Impact on health behaviour: 6MWD · the management of chronic obstructive pulmonary disease
Digital interventions for the management of chronic obstructive pulmonary disease (2021) · Cochrane
no estimate extracted1 study · 20 participantsVery low
Multi‐component intervention vs other intervention or routine, usual care or control treatment
Quality of life: SGRQ total · the management of chronic obstructive pulmonary disease
Digital interventions for the management of chronic obstructive pulmonary disease (2021) · Cochrane
no estimate extracted3 studies · 241 participantsVery low
Multi‐component intervention vs other intervention or routine, usual care or control treatment
Exacerbations: number of people experiencing at least one exacerbation · the management of chronic obstructive pulmonary disease
Digital interventions for the management of chronic obstructive pulmonary disease (2021) · Cochrane
OR 0.86 [0.58, 1.28]2 studies · 485 participantsVery low
Single component intervention vs control
Adherence to pharmacotherapy: number of people completing treatment · COPD
Interventions to improve adherence to pharmacological therapy for chronic obstructive pulmonary disease (COPD) (2021) · Cochrane
OR 0.67 [0.22, 1.99]1 study · 55 participantsLow
Multi‐component intervention vs control
Adverse events: number of people experiencing adverse events (all cause or COPD‐related), serious adverse events, mortality · COPD
Interventions to improve adherence to pharmacological therapy for chronic obstructive pulmonary disease (COPD) (2021) · Cochrane
OR 1.05 [0.6, 1.85]1 study · 192 participantsLow
Single component intervention vs control
Quality of life: SGRQ total or CCQ · COPD
Interventions to improve adherence to pharmacological therapy for chronic obstructive pulmonary disease (COPD) (2021) · Cochrane
no estimate extracted1 study · 212 participantsVery low
Single component intervention vs control
Hospital service utilisation: number of people admitted to hospital (all cause) · COPD
Interventions to improve adherence to pharmacological therapy for chronic obstructive pulmonary disease (COPD) (2021) · Cochrane
OR 1.47 [0.75, 2.9]1 study · 212 participantsVery low
Single component intervention vs control
Exacerbations: number of people experiencing exacerbations · COPD
Interventions to improve adherence to pharmacological therapy for chronic obstructive pulmonary disease (COPD) (2021) · Cochrane
OR 0.87 [0.51, 1.5]2 studies · 267 participantsVery low
Single component intervention vs control
Adverse events: number of people experiencing adverse events (all cause or COPD‐related), serious adverse events, mortality · COPD
Interventions to improve adherence to pharmacological therapy for chronic obstructive pulmonary disease (COPD) (2021) · Cochrane
OR 0.92 [0.6, 1.41]3 studies · 404 participantsVery low