Findings

What do systematic reviews say?

492 questions · 535 findings · 56 reviews · Hypertension

Sort:Best matchNewestHighest certainty Download CSV

No studies found 37 · 6.9%GRADE not reported 34 · 6.4%Very low 91 · 17%Low 161 · 30.1%Moderate 136 · 25.4%High 76 · 14.2%

Intervention not reported

0.3 mg/d · participants with normal or abnormal lipid profiles

1 finding from 1 review

Cerivastatin for lowering lipids 2020 · Cochrane Headline outcomes only
no estimate extracted
19 studies · 3020 participants
High

Intervention not reported

0.4 mg/d · participants with normal or abnormal lipid profiles

1 finding from 1 review

Cerivastatin for lowering lipids 2020 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 3080 participants
High

Intervention not reported

0.8 mg/d · participants with normal or abnormal lipid profiles

1 finding from 1 review

Cerivastatin for lowering lipids 2020 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 2560 participants
High

Intervention not reported

aMean baseline values. · participants with normal or abnormal lipid profiles

The review found no eligible studies for this question.

1 finding from 1 review

Cerivastatin for lowering lipids 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Cerivastatin dose · participants with normal or abnormal lipid profiles

The review found no eligible studies for this question.

1 finding from 1 review

Cerivastatin for lowering lipids 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Renin inhibitors vs ACE inhibitor

All‐cause mortality · people with primary hypertension

Renin inhibitors showed no clear difference in all‐cause mortality compared with ACE inhibitors (low certainty).

1 finding from 1 review

Renin inhibitors versus angiotensin converting enzyme (ACE) inhibitors for primary hypertension 2020 · Cochrane Headline outcomes only
RR 1.05 [0.93, 1.18]
5 studies · 5962 participants
Low

Renin inhibitors vs ACE inhibitor

Fatal or nonfatal myocardial infarction · people with primary hypertension

It is very uncertain whether renin inhibitors changes fatal or non‐fatal myocardial infarction compared with ACE inhibitors (very low certainty).

1 finding from 1 review

Renin inhibitors versus angiotensin converting enzyme (ACE) inhibitors for primary hypertension 2020 · Cochrane Headline outcomes only
RR 0.86 [0.22, 3.39]
2 studies · 957 participants
Very low

Renin inhibitors vs ACE inhibitor

Adverse events · people with primary hypertension

Renin inhibitors showed no clear difference in adverse events compared with ACE inhibitors (moderate certainty).

1 finding from 1 review

Renin inhibitors versus angiotensin converting enzyme (ACE) inhibitors for primary hypertension 2020 · Cochrane Headline outcomes only
RR 0.98 [0.93, 1.03]
10 studies · 6007 participants
Moderate

Renin inhibitors vs ACE inhibitor

Fatal or non‐fatal serious adverse events · people with primary hypertension

Renin inhibitors showed no clear difference in fatal or non‐fatal serious adverse events compared with ACE inhibitors (low certainty).

1 finding from 1 review

Renin inhibitors versus angiotensin converting enzyme (ACE) inhibitors for primary hypertension 2020 · Cochrane Headline outcomes only
RR 1.21 [0.89, 1.64]
10 studies · 6007 participants
Low

Renin inhibitors vs ACE inhibitor

WDAEs · people with primary hypertension

Renin inhibitors showed no clear difference in withdrawal due to adverse effects (WDAE) compared with ACE inhibitors (low certainty).

1 finding from 1 review

Renin inhibitors versus angiotensin converting enzyme (ACE) inhibitors for primary hypertension 2020 · Cochrane Headline outcomes only
RR 0.85 [0.68, 1.06]
10 studies · 6008 participants
Low

Renin inhibitors vs ACE inhibitor

Systolic blood pressure · people with primary hypertension

1 finding from 1 review

Renin inhibitors versus angiotensin converting enzyme (ACE) inhibitors for primary hypertension 2020 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 5001 participants
Low

Renin inhibitors vs ACE inhibitor

Diastolic blood pressure · people with primary hypertension

1 finding from 1 review

Renin inhibitors versus angiotensin converting enzyme (ACE) inhibitors for primary hypertension 2020 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 5001 participants
Low

Discontinuation by no treatment/placebo of antihypertensives vs continuation

All‐cause mortality · Older adults, 50 years and older

Discontinuation by no treatment/placebo of antihypertensives showed no clear difference in all‐cause mortality compared with continuation (low certainty).

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
OR 2.08 [0.79, 5.46]
4 studies · 630 participants
Low

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Fatal or nonfatal myocardial infarction · Older adults, 50 years and older

It is very uncertain whether discontinuation by no treatment/placebo of antihypertensives changes myocardial infarction (fatal and nonfatal) compared with continuation (very low certainty).

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
OR 1.86 [0.19, 17.98]
2 studies · 447 participants
Very low

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Hospital admissions · Older adults, 50 years and older

Discontinuation by no treatment/placebo of antihypertensives showed no clear difference in hospitalisation compared with continuation (low certainty).

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
OR 0.83 [0.33, 2.1]
1 study · 385 participants
Low

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Stroke (fatal + nonfatal + TIA) · Older adults, 50 years and older

Discontinuation by no treatment/placebo of antihypertensives showed no clear difference in stroke (fatal + nonfatal + TIA) compared with continuation (low certainty).

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
OR 1.44 [0.25, 8.35]
3 studies · 524 participants
Low

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Systolic blood pressure · Older adults, 50 years and older

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 767 participants
Low

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Diastolic blood pressure · Older adults, 50 years and older

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 768 participants
Low

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Adverse drug reactions and adverse drug withdrawal reactions (adverse reactions) · Older adults, 50 years and older

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 245 participants
Very low

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Falls ‐ not reported · Older adults, 50 years and older

The review found no eligible studies for this question.

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found