Participant‐reported pain relief of 50% or greater · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…
Paracetamol (single oral dose, any dose or formulation; subgroups up… led to higher achieving at least 50% pain relief at 6 hours (using pain relief… compared with placebo; GRADE not reported.
1 finding from 1 review
Pocket closure · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
2 findings from 1 review
Three studies evaluated the proportion of closed pockets three months after treatment (Al-Zahrani 2011; Courval 2020; Rodrigues 2023); studies used different criteria to measure this outcome. All studies reported an…
3 studies
GRADE not reported
No studies measured this outcome at 6 months (SoF row labeled 'Change in pocket depth from baseline to 6 months after initial treatment').
Studies not reported
No studies found
Perceived need for surgery in adulthood · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
The review found no eligible studies for this question.
1 finding from 1 review
Patient satisfaction · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
The review found no eligible studies for this question.
1 finding from 1 review
Any adverse effect related to aPDT · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
1 finding from 1 review
Risk with control: 23 studies reported that no adverse effects of aPDT were observed. Number of participants (studies): 639 (24 studies). Certainty: Moderate. (24 studies reported adverse effects, with all studies…
24 studies · 639 participants
Moderate
Change in probing pocket depth (PPD) · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after… led to higher change in probing pocket depth (PPD) compared with subgingival instrumentation (SI) alone (hand or power-driven, or…; GRADE not reported.
2 findings from 1 review
Attachment change · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after… led to higher change in clinical attachment level (CAL) compared with subgingival instrumentation (SI) alone (hand or power-driven, or…; GRADE not reported.
2 findings from 1 review
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
It is very uncertain whether facemask (RME) or modified facemask changes ANB compared with other non-surgical orthodontic treatments (mini maxillary… (very low certainty).
1 finding from 1 review
Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
It is very uncertain whether facemask (RME) or modified facemask changes overjet compared with surgically-anchored appliance (miniscrews or miniplates) (very low certainty).
1 finding from 1 review
Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask (RME) or modified facemask showed no clear difference in wits appraisal compared with surgically-anchored appliance (miniscrews or miniplates); GRADE not reported.
1 finding from 1 review
Change in bleeding on probing (BOP) · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
It is very uncertain whether adjunctive antimicrobial photodynamic therapy (aPDT) applied after… changes change in bleeding on probing (BOP) compared with subgingival instrumentation (SI) alone (hand or power-driven, or… (very low certainty).
2 findings from 1 review
Perceived need for surgery in adulthood · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
The review found no eligible studies for this question.
1 finding from 1 review
Quality of life · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
The review found no eligible studies for this question.
1 finding from 1 review
Change in gingival recession (REC) · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
It is very uncertain whether adjunctive antimicrobial photodynamic therapy (aPDT) applied after… changes change in gingival recession (REC) compared with subgingival instrumentation (SI) alone (hand or power-driven, or… (very low certainty).
2 findings from 1 review
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask (RME) or modified facemask showed no clear difference in ANB compared with surgically-anchored appliance (miniscrews or miniplates) (low certainty).
1 finding from 1 review
Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
It is very uncertain whether facemask (RME) or modified facemask changes overjet compared with other non-surgical orthodontic treatments (mini maxillary… (very low certainty).
1 finding from 1 review
Healing of MRONJ (mucosal integrity) · People with MRONJ referred for surgical treatment
It is very uncertain whether autofluorescence-guided bone surgery changes healing of MRONJ (mucosal integrity) compared with tetracycline fluorescence-guided bone surgery (very low certainty).
1 finding from 1 review
Sensitivity · Adults (aged 16 years or over) presenting to primary or secondary care with clinically evident suspicious or innocuous oral lesions
1 finding from 1 review
Blood and saliva analysis (biomarker tests) vs Surgical or punch biopsy with histological assessment
Outcome not reported · Adults (aged 16 years or over) presenting to primary or secondary care with clinically evident suspicious or innocuous oral lesions
The review found no eligible studies for this question.
1 finding from 1 review
Specificity · Adults (aged 16 years or over) presenting to primary or secondary care with clinically evident suspicious or innocuous oral lesions
1 finding from 1 review