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What do systematic reviews say?

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Evidence found and GRADE certainty

583 questions · 638 findings · 60 reviews · Infectious Diseases

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No studies found 54 · 8.5%GRADE not reported 98 · 15.4%Very low 118 · 18.5%Low 141 · 22.1%Moderate 141 · 22.1%High 86 · 13.5%

Intervention not reported

Stillbirth · HIV‐positive women during pregnancy and immediate postpartum period

It is very uncertain whether the intervention changes stillbirth (very low certainty).

1 finding from 1 review

Intervention not reported

Maternal death · HIV‐positive women during pregnancy and immediate postpartum period

It is very uncertain whether the intervention changes maternal death (very low certainty).

1 finding from 1 review

BivWC vaccine (Shanchol): two doses vs placebo

Cases of cholera ( · healthy children and adults; high risk population
3 findings from 1 review

Intervention not reported

Non‐randomized studies** · adults and children

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Non‐randomized studies** · adults and children

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Non‐randomized studies** · adults and children

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

All‐cause mortality at day 28 · unvaccinated, non‐hospitalized people with mild symptomatic COVID‐19 (WHO scale 2 to 3) at high risk for progression to severe disease

The intervention may leads to lower all‐cause mortality at day 28 (low certainty).

1 finding from 1 review

Intervention not reported

Discontinuation of study drug due to adverse events · unvaccinated, non‐hospitalized people with mild symptomatic COVID‐19 (WHO scale 2 to 3) at high risk for progression to severe disease

The intervention probably leads to lower discontinuation of study drug due to adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Viral clearance at 14 days · unvaccinated, non‐hospitalized people with mild symptomatic COVID‐19 (WHO scale 2 to 3) at high risk for progression to severe disease

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

All‐cause mortality at day 28 · hospitalized people with mild to moderate symptomatic COVID‐19 (WHO scale 2 to 4) with severe comorbidities

It is very uncertain whether the intervention changes all‐cause mortality at day 28 (very low certainty).

1 finding from 1 review