Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,429 questions · 3,558 findings · 436 reviews

No studies found 660 · 18.5%GRADE not reported 375 · 10.5%Very low 727 · 20.4%Low 887 · 24.9%Moderate 709 · 19.9%High 200 · 5.6%

Manipulative therapy vs control condition

Presence/absence of colic Global impression of change scale completed by parents · infants with colic defined by recognised criteria

Manipulative therapy showed no clear difference in presence/absence of colic Global impression of change scale… compared with control condition (low certainty).

1 finding from 1 review

Manipulation (cervical) vs oral medicine

Acute and subacute neck pain Intermediate‐term · patients with acute and subacute neck pain

Manipulation (cervical) showed no clear difference in acute and subacute neck pain Intermediate‐term compared with oral medicine (moderate certainty).

1 finding from 1 review

Manipulation (thoracic) vs inactive control

Acute and subacute neck pain Short‐term · patients with acute, subacute and chronic neck pain

Manipulation (thoracic) showed no clear difference in acute and subacute neck pain Short‐term compared with inactive control (moderate certainty).

1 finding from 1 review