evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,155 questions · 1,191 findings · 195 reviews · Headline outcomes only

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 209 · 17.5%GRADE not reported 51 · 4.3%Very low 256 · 21.5%Low 273 · 22.9%Moderate 284 · 23.8%High 118 · 9.9%

Pregabalin vs placebo

Maintenance of initial therapeutic response of at least 30% pain intensity reduction over baseline and continued treatment at 13 or 26 weeks (equivalent to 'moderate benefit') · adults with fibromyalgia enrolled in EERW studies
1 finding from 1 review

Trapeziectomy with interpositional arthroplasty (T and IA) vs Artelon joint resurfacing

Adverse events Mild to moderate swelling · Patients with thumb (trapeziometacarpal joint) osteoarthritis

It is very uncertain whether trapeziectomy with interpositional arthroplasty (T and IA) changes adverse events Mild to moderate swelling compared with artelon joint resurfacing (very low certainty).

1 finding from 1 review

Quinine vs placebo

Cramp intensity (on 3‐point scale; 1 = mild; 2 = moderate; 3 = severe) · patients with muscle cramps
1 finding from 1 review

Quinine vs vitamin E

Cramp intensity (on 3‐point scale; 1 = mild; 2 = moderate; 3 = severe) · patients with muscle cramps
1 finding from 1 review

Intervention not reported

Co‐operation during induction ‐ Video 'fairytale' vs. no audiovisual aid (Passive) ICC = 0 (perfect vs. poor‐moderate compliance) · children

It is very uncertain whether the intervention changes co‐operation during induction ‐ Video 'fairytale' vs. no audiovisual… (very low certainty).

1 finding from 1 review

Intervention not reported

Moderate to severe pain at IUC insertion (dichotomous) · women with IUC being inserted

The intervention may leads to lower moderate to severe pain at IUC insertion (dichotomous) (low certainty).

1 finding from 1 review

DCS and cognitive and behavioural therapies vs placebo and cognitive and behavioural therapies

Condition‐specific anxiety symptoms As assessed by LSAS5 (scale from: 0 to 144, better indicated by a lower score. 55 to 65 points = moderate social anxiety disorder (Liebowitz 1987)) · adults with anxiety disorders

DCS and cognitive and behavioural therapies showed no clear difference in condition‐specific anxiety symptoms As assessed by LSAS5 (scale… compared with placebo and cognitive and behavioural therapies (moderate certainty).

1 finding from 1 review

DCS and cognitive and behavioural therapies vs placebo and cognitive and behavioural therapies

Anxiety · adults with anxiety disorders

DCS and cognitive and behavioural therapies showed no clear difference in co‐morbid anxiety symptoms As assessed by BAI9 (scale from: 0 to 63,… compared with placebo and cognitive and behavioural therapies (low certainty).

1 finding from 1 review

Intervention not reported

At least 30% reduction in pain or equivalent (moderate) · adults with fibromyalgia
1 finding from 1 review

Intervention not reported

Physical activity Average daily minutes of moderate to vigorous (24 months) · whole communities (adults, adolescents and children)
1 finding from 1 review

Tramadol vs pethidine

Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery

Tramadol showed no clear difference in number of patients with moderate to severe pain (PACU) compared with pethidine (low certainty).

1 finding from 1 review

Tramadol vs fentanyl

Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery

The review found no eligible studies for this question.

1 finding from 1 review

Tramadol vs morphine

Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery

The review found no eligible studies for this question.

1 finding from 1 review