zBMI short term (12 weeks from baseline to < 9 months) · children aged 5 to 11 years
1 finding from 1 review
zBMI medium term (9 months to < 15 months) · children aged 5 to 11 years
1 finding from 1 review
zBMI long term (> 15 months) · children aged 5 to 11 years
1 finding from 1 review
Serious adverse events · children aged 5 to 11 years
1 finding from 1 review
Body‐mass index (BMI) · children aged 12 to 18 years
3 findings from 1 review
no estimate extracted
3 studies · 605 participants
Very low
no estimate extracted
3 studies · 900 participants
Very low
no estimate extracted
1 study · 44 participants
Low
zBMI short term (12 weeks from baseline to < 9 months) · children aged 12 to 18 years
1 finding from 1 review
zBMI medium term (9 months to < 15 months) · children aged 12 to 18 years
1 finding from 1 review
zBMI long term (> 15 months) · children aged 12 to 18 years
1 finding from 1 review
Serious adverse events · children aged 12 to 18 years
1 finding from 1 review
Harmful alcohol use · alcohol use disorder
2 findings from 1 review
Retention [ · alcohol use disorder
Pharmacologic intervention along with psychosocial intervention showed no clear difference in retention compared with psychosocial intervention alone (moderate certainty).
1 finding from 1 review
Live birth · obese women with subfertility
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events ‐ Metformin plus liraglutide vs metformin Nausea Diarrhoea Headache · obese women with subfertility
It is very uncertain whether pharmacological intervention changes adverse events ‐ Metformin plus liraglutide vs metformin Nausea… compared with pharmacological intervention (very low certainty).
1 finding from 1 review
Clinical pregnancyMetformin plus liraglutide vs metformin Met + CC + L‐carnitine vs Met + CC + placebo · obese women with subfertility
It is very uncertain whether pharmacological intervention changes clinical pregnancyMetformin plus liraglutide vs metformin Met + CC +… compared with pharmacological intervention (very low certainty).
1 finding from 1 review
MiscarriageMet + CC + L‐carnitine vs Met + CC + placebo · obese women with subfertility
It is very uncertain whether pharmacological intervention changes miscarriageMet + CC + L‐carnitine vs Met + CC + placebo compared with pharmacological intervention (very low certainty).
1 finding from 1 review
Weight ‐ BMI changeMetformin plus liraglutide vs metformin Met + CC + L‐carnitine vs Met + CC + placebo Weight changeDexfenfluramine vs placebo Weight ‐ body fatMetformin plus liraglutide vs metformin · obese women with subfertility
1 finding from 1 review
Quality of life/Mental health outcome · obese women with subfertility
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Live birth · obese women with subfertility
It is very uncertain whether pharmacological intervention changes live birth compared with no intervention or placebo (very low certainty).
1 finding from 1 review
Ongoing pregnancy · obese women with subfertility
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Miscarriage · obese women with subfertility
It is very uncertain whether pharmacological intervention changes miscarriage compared with no intervention or placebo (very low certainty).
1 finding from 1 review