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Evidence found and GRADE certainty

269 questions · 269 findings · 25 reviews · Hepato-Biliary

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No studies found 87 · 32.3%GRADE not reported 0 · 0%Very low 117 · 43.5%Low 48 · 17.8%Moderate 14 · 5.2%High 3 · 1.1%

Intervention not reported

All‐cause mortality or liver‐related morbidity · patients with chronic hepatitis C

It is very uncertain whether the intervention changes all‐cause mortality or liver‐related morbidity (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse events · patients with chronic hepatitis C

The intervention showed no clear difference in adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Failure of end of treatment virological response Absence of clearance of HCV RNA from the blood at end of treatment · patients with chronic hepatitis C

The intervention showed no clear difference in failure of end of treatment virological response Absence of… (moderate certainty).

1 finding from 1 review

Intervention not reported

Failure of sustained virological response Absence of clearance of HCV RNA from the blood 6 months after treatment · patients with chronic hepatitis C

The intervention showed no clear difference in failure of sustained virological response Absence of clearance of… (moderate certainty).

1 finding from 1 review

Intervention not reported

Quality of life Different QoL scales · patients with chronic hepatitis C
1 finding from 1 review

Intervention not reported

Failure of normalisation of ALT at end of treatment · patients with chronic hepatitis C

The intervention may leads to lower failure of normalisation of ALT at end of treatment (low certainty).

1 finding from 1 review

Intervention not reported

Failure of normalisation of ALT at end of · patients with chronic hepatitis C

The intervention showed no clear difference in failure of normalisation of ALT at end of (low certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality or liver‐related morbidity · patients with chronic hepatitis C.

It is very uncertain whether the intervention changes all‐cause mortality or liver‐related morbidity (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse events · patients with chronic hepatitis C.

It is very uncertain whether the intervention changes adverse events (very low certainty).

1 finding from 1 review

Intervention not reported

Failure of sustained virological response Absence of clearance of HCV RNA from the blood 6 months after treatment · patients with chronic hepatitis C.

The intervention may leads to higher failure of sustained virological response Absence of clearance of… (low certainty).

1 finding from 1 review

Intervention not reported

Failure of end of treatment virological response Absence of clearance of HCV RNA from the blood at end of treatment · patients with chronic hepatitis C.

The intervention may leads to higher failure of end of treatment virological response Absence of… (low certainty).

1 finding from 1 review

Intervention not reported

Failure of normalisation of ALT at end of treatment · patients with chronic hepatitis C.

It is very uncertain whether the intervention changes failure of normalisation of ALT at end of treatment (very low certainty).

1 finding from 1 review

Intervention not reported

Failure of normalisation of ALT at end of · patients with chronic hepatitis C.

It is very uncertain whether the intervention changes failure of normalisation of ALT at end of (very low certainty).

1 finding from 1 review