Findings

What do systematic reviews say?

395 questions · 404 findings · 37 reviews · Headline outcomes only

Sort:Best matchNewest Highest certainty Download CSV

No studies found 83 · 20.5%GRADE not reported 41 · 10.1%Very low 127 · 31.4%Low 115 · 28.5%Moderate 38 · 9.4%High 0 · 0%

Sertraline vs cognitive behavioural therapy

> 50% reduction in depressive symptoms · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Sertraline vs cognitive behavioural therapy

Depressive symptoms · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 117 participants
Moderate

Sertraline vs cognitive behavioural therapy

Seizure frequency · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 96 participants
Low

Sertraline vs cognitive behavioural therapy

Treatment withdrawal · people with epilepsy and depression

Sertraline showed no clear difference in withdrawals compared with cognitive behavioural therapy (moderate certainty).

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
RR 1.26 [0.64, 2.46]
1 study · 140 participants
Moderate

Sertraline vs cognitive behavioural therapy

Quality of life (QOLIE‐89) (1‐ to 3‐month periods) · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 118 participants
Moderate

Sertraline vs cognitive behavioural therapy

Adverse effects · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 118 participants
Low

Selective serotonin reuptake inhibitors vs cognitive behavioural therapy

> 50% reduction in depressive symptoms · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Selective serotonin reuptake inhibitors vs cognitive behavioural therapy

Depressive symptoms · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
15 participants
Very low

Selective serotonin reuptake inhibitors vs cognitive behavioural therapy

Seizure frequency · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
15 participants
Very low

Selective serotonin reuptake inhibitors vs cognitive behavioural therapy

Treatment withdrawal · people with epilepsy and depression

It is very uncertain whether selective serotonin reuptake inhibitors changes withdrawals compared with cognitive behavioural therapy (very low certainty).

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
RR 0.44 [0.05, 3.85]
15 participants
Very low

Selective serotonin reuptake inhibitors vs cognitive behavioural therapy

Post‐treatment quality of life (QOLIE‐31 score, which has a range of 0‐200, with higher score indicates better quality of life) ( · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
15 participants
Very low

Selective serotonin reuptake inhibitors vs cognitive behavioural therapy

Adverse effects ‐ adverse event profile · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

CBT vs treatment

Reduction in anxiety symptoms (parent report) post‐treatment · children and adolescents with anxiety disorders

2 findings from 2 reviews · compare the 2 reviews

Cognitive behavioural therapy for anxiety disorders in children and adolescents 2020 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 228 participants
Low
Cognitive behavioural therapy for anxiety disorders in children and adolescents 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 98 participants
Moderate

CBT vs WAIT LIST

Reduction in anxiety symptoms (parent report) post‐treatment · children and adolescents with anxiety disorders

3 findings from 2 reviews · compare the 2 reviews

Cognitive behavioural therapy for anxiety disorders in children and adolescents 2020 · Cochrane Headline outcomes only
no estimate extracted
35 studies · 2137 participants
Low
Cognitive behavioural therapy for anxiety disorders in children and adolescents 2015 · Cochrane Headline outcomes only
no estimate extracted
30 studies · 1394 participants
Low
Cognitive behavioural therapy for anxiety disorders in children and adolescents 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 186 participants
Low

Summary of findings table ‐ CBT without antipsychotics vs no specific treatment

Mental state · schizophrenia

1 finding from 1 review

Cognitive behavioural therapy without medication for schizophrenia 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Summary of findings table ‐ CBT without antipsychotics vs antipsychotics

Risk for at least one adverse event per patient · schizophrenia

It is very uncertain whether summary of findings table ‐ CBT without antipsychotics changes adverse events ‐ Participants with at least one AE (separated time… compared with antipsychotics (very low certainty).

1 finding from 1 review

Cognitive behavioural therapy without medication for schizophrenia 2024 · Cochrane Headline outcomes only
RR 0.47 [0.21, 1.07]
1 study · 40 participants
Very low

Summary of findings table ‐ CBT without antipsychotics vs CBT plus antipsychotics

Mental state · schizophrenia

1 finding from 1 review

Cognitive behavioural therapy without medication for schizophrenia 2024 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 125 participants
Very low

Summary of findings table ‐ CBT without antipsychotics vs CBT plus antipsychotics

Global state ‐ number of participants with relapse/exacerbations of psychosis (separated time points) ‐ < 12 months · schizophrenia

It is very uncertain whether summary of findings table ‐ CBT without antipsychotics changes global state ‐ number of participants with relapse/exacerbations of… compared with CBT plus antipsychotics (very low certainty).

1 finding from 1 review

Cognitive behavioural therapy without medication for schizophrenia 2024 · Cochrane Headline outcomes only
RR 2.89 [0.12, 67.75]
1 study · 90 participants
Very low

Summary of findings table ‐ CBT without antipsychotics vs CBT plus antipsychotics

Leaving the study early/ loss to · schizophrenia

It is very uncertain whether summary of findings table ‐ CBT without antipsychotics changes leaving the study early ‐ for any reason ‐ overall acceptability… compared with CBT plus antipsychotics (very low certainty).

1 finding from 1 review

Cognitive behavioural therapy without medication for schizophrenia 2024 · Cochrane Headline outcomes only
RR 0.7 [0.12, 4.11]
2 studies · 90 participants
Very low

Summary of findings table ‐ CBT without antipsychotics vs CBT plus antipsychotics

Level of functioning · schizophrenia

1 finding from 1 review

Cognitive behavioural therapy without medication for schizophrenia 2024 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 110 participants
Very low