Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

574 questions · 721 findings · 67 reviews

No studies found 93 · 12.9%GRADE not reported 450 · 62.4%Very low 82 · 11.4%Low 73 · 10.1%Moderate 21 · 2.9%High 2 · 0.3%

Silver diamine fluoride (SDF) vs Atraumatic restorative treatment (ART) with glass ionomer cement (GIC) or glass ionomer material

Caries arrest · Children and adults (with or without carious lesions)

The review found no eligible studies for this question.

2 findings from 1 review

Laser enamel preparation alone (Er,Cr:YSGG or CO2 laser) vs Acid-etching (phosphoric acid)

Development of >=1 new carious lesion (caries incidence) · Caries-free children to young adults with premolars/molars requiring pit-and-fissure sealants

In the single study reporting it, caries incidence was 0% in both the laser-alone and acid-etching groups (ungraded, single study).

1 finding from 1 review

Intervention not reported

Dental caries prevalence in primary teeth (cavitated lesions) · Children aged 5-6 years in Latin America and the Caribbean

In other Latin American/Caribbean countries, pooled primary-teeth caries prevalence was 70% (95% CI 59-79%), significantly higher than Brazil (p=0.002); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence in permanent teeth (cavitated lesions) · Children aged 11-13 years in Latin America and the Caribbean

In other Latin American/Caribbean countries, pooled permanent-teeth caries prevalence was 64% (95% CI 45-79%), not significantly different from Brazil (p=0.42); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence in primary teeth (cavitated lesions) · Children aged 5-6 years in Latin America and the Caribbean

In Brazil, pooled primary-teeth caries prevalence in 5-6 year-olds was 52% (95% CI 49-54%); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence in primary teeth (cavitated lesions) · Children aged 5-6 years in Latin America and the Caribbean

About 56% of 5-6 year-old children in Latin America and the Caribbean had dental caries in primary teeth (95% CI 52-59%); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence in permanent teeth (cavitated lesions) · Children aged 11-13 years in Latin America and the Caribbean

In Brazil, pooled permanent-teeth caries prevalence in 11-13 year-olds was 56% (95% CI 53-60%), with a significant declining trend over time; certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence in permanent teeth (cavitated lesions) · Children aged 11-13 years in Latin America and the Caribbean

About 58% of 11-13 year-old children in Latin America and the Caribbean had dental caries in permanent teeth (95% CI 54-61%); certainty not graded.

1 finding from 1 review

Xylitol sucking tablets (1 g/day) vs no treatment

Number of infants with a caries increment · Infants/young children (primary teeth; baseline about 1 to 3 years)

Xylitol sucking tablets (1 g/day) showed no clear difference in number of infants with a caries increment compared with no treatment; GRADE not reported.

1 finding from 1 review

Chlorhexidine varnish (10% and 40%) vs placebo or no treatment

Caries increment in permanent teeth · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

It is very uncertain whether chlorhexidine varnish (10% and 40%) changes caries increment in permanent dentition (DMFS; higher values… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Chlorhexidine gel (0.12%) vs no treatment

Presence of new caries in the primary teeth · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

It is very uncertain whether chlorhexidine gel (0.12%) changes presence of new caries in the primary teeth compared with no treatment (very low certainty).

1 finding from 1 review

Chlorhexidine varnish vs placebo or no treatment

Dental caries: dmfs increment (primary teeth) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
1 finding from 1 review

Fluoride supplementation (tablets, drops, lozenges or chewing gum) vs Topical fluoride (fluoride rinse, varnish or toothpaste)

Fluorosis (adverse effect; % of children with fluorotic teeth) · Children and adolescents aged 16 years or less

The review found no eligible studies for this question.

1 finding from 1 review

Fluoride supplementation (tablets, drops, lozenges or chewing gum) vs No fluoride supplement (placebo or no treatment)

Fluorosis (adverse effect; % of children with fluorotic teeth, questionable to severe) · Children and adolescents aged 16 years or less
1 finding from 1 review

Dental fillings (restorations) vs Dental extractions

Outcome not reported · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic or symptom free

The review found no eligible studies for this question.

1 finding from 1 review

Individually designed, patient-centred preventive programme: dietary counselling (snacking timing, regular meals, fermentable carbohydrates) plus toothbrushing counselling, delivered by trained dental hygienists (a multi-intervention) vs Basic prevention offered as standard in public dental clinics

Nibbling less than daily · Children aged 11 to 12 years with at least one active initial caries lesion, screened in a town in Finland
1 finding from 1 review

Individually designed, patient-centred preventive programme: dietary counselling (snacking timing, regular meals, fermentable carbohydrates) plus toothbrushing counselling, delivered by trained dental hygienists (a multi-intervention) vs Basic prevention offered as standard in public dental clinics

Eating candy less than daily · Children aged 11 to 12 years with at least one active initial caries lesion, screened in a town in Finland
1 finding from 1 review

Individually designed, patient-centred preventive programme: dietary counselling (snacking timing, regular meals, fermentable carbohydrates) plus toothbrushing counselling, delivered by trained dental hygienists (a multi-intervention) vs Basic prevention offered as standard in public dental clinics

Drinking soft drinks less than daily · Children aged 11 to 12 years with at least one active initial caries lesion, screened in a town in Finland
1 finding from 1 review