Question · asked by 1 review

Fluoride supplementation (tablets, drops, lozenges or chewing gum) vs No fluoride supplement (placebo or no treatment): Fluorosis (adverse effect; % of children with fluorotic teeth, questionable to severe)

Population
Children and adolescents aged 16 years or less
Intervention
Fluoride supplementation (tablets, drops, lozenges or chewing gum)
Comparison
No fluoride supplement (placebo or no treatment)
Outcome
Fluorosis (adverse effect; % of children with fluorotic teeth, questionable to severe)

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Fluoride supplements (tablets, drops, lozenges or chewing gums) vs No fluoride supplement (placebo or no treatment)
Fluorosis (adverse effect; % of children with fluorotic teeth, questionable to severe) · Children and adolescents (aged 16 years or less at baseline) · 55 months
Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children (2011) · Cochrane All outcomes
% of children with fluorotic teeth (questionable to severe), follow-up 55 months. Assumed risk 32/212 = 15%; corresponding risk 40/202 = 20% (APF once a day) and 43/197 = 22% (APF twice a day). Relative effect: Not…1 study · 611 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children
2011 · Cochrane All outcomes
2011-10Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.