Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,123 questions · 2,188 findings · 243 reviews

No studies found 493 · 22.5%GRADE not reported 160 · 7.3%Very low 600 · 27.4%Low 474 · 21.7%Moderate 364 · 16.6%High 97 · 4.4%

Antibiotics vs placebo

Clinical failure · acute rhinosinusitis in adults, whether clinically diagnosed or confirmed by imaging

Antibiotics leads to lower clinical failure compared with placebo (high certainty).

1 finding from 1 review

Antibiotics vs placebo

Treatment failure within 4 weeks ‐ current drugs only ‐ inpatient · exacerbations of COPD

Antibiotics showed no clear difference in treatment failure within 4 weeks ‐ current drugs only ‐ inpatient compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotics vs placebo

Total postoperative infections ‐ early and late · women having elective vaginal hysterectomy

Antibiotics may leads to lower total postoperative infections ‐ early and late compared with placebo (low certainty).

1 finding from 1 review