Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

291 questions · 293 findings · 75 reviews

No studies found 56 · 19.1%GRADE not reported 24 · 8.2%Very low 61 · 20.8%Low 62 · 21.2%Moderate 39 · 13.3%High 51 · 17.4%

Intervention not reported

ASCVD event, such as fatal or non‐fatal myocardial infarction or stroke. Median · adults older than 18 years, with no restriction regarding presence of ASCVD; participants generally had elevated risk of ASCVD (as…

The intervention showed no clear difference in ASCVD event, such as fatal or non‐fatal myocardial infarction or… (low certainty).

1 finding from 1 review

Intervention not reported

Any investigator‐defined adverse event Median · adults older than 18 years, with no restriction regarding presence of ASCVD; participants generally had elevated risk of ASCVD (as…

The intervention probably leads to higher any investigator‐defined adverse event Median (moderate certainty).

1 finding from 1 review

Intervention not reported

Adherence, variable definitions Median · adults older than 18 years, with no restriction regarding presence of ASCVD; participants generally had elevated risk of ASCVD (as…

The intervention probably leads to higher adherence, variable definitions Median (moderate certainty).

1 finding from 1 review

Intervention not reported

LDL‐cholesterol atorvastatin 10 mg/d · individuals with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

LDL‐cholesterol atorvastatin 20 mg/d · individuals with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

LDL‐cholesterol atorvastatin 40 mg/d · individuals with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

LDL‐cholesterol atorvastatin 80 mg/d · individuals with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

WDAEb all doses · individuals with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

LDL‐Cholesterol rosuvastatin 2.5 mg/day · participantswith normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

LDL‐Cholesterol rosuvastatin 5 mg/day · participantswith normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

LDL‐Cholesterol rosuvastatin 10 mg/day · participantswith normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

LDL‐Cholesterol rosuvastatin 20 mg/day · participantswith normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

LDL‐Cholesterol rosuvastatin 40 mg/day · participantswith normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

WDAE2 all doses · participantswith normal or abnormal lipid profiles
1 finding from 1 review