Findings

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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Late treatment (one-phase) with removable functional appliance vs no treatment

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Late treatment (one-phase) with removable functional appliance may leads to lower final overjet compared with no treatment (low certainty).

1 finding from 1 review

1.5% HP + 0.05% HF mouthwash vs placebo

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 1.5% HP + 0.05% HF mouthwash changes tooth whitening - assessed by the dentist compared with placebo (very low certainty).

1 finding from 1 review

SPT performed by non-specialist clinicians (general dental practitioners under specialist prescription) vs SPT performed by specialists (specialist practice)

Periodontitis (clinical attachment loss) · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)

The review found no eligible studies for this question.

1 finding from 1 review

Calcium hydroxide (CH) vs Mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) led to higher radiological failure compared with mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl); GRADE not reported.

1 finding from 1 review

Autologous platelet concentrates (APC) + open flap debridement (OFD) vs Open flap debridement (access flap surgery)

Change in radiographic bone defect filling (RBF) (%) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD) changes change in radiographic bone defect filling (RBF) (%) compared with OFD (open flap debridement) alone (very low certainty).

1 finding from 1 review

Autologous platelet concentrates (APC) + guided tissue regeneration (GTR) vs GTR (guided tissue regeneration) alone

Change in radiographic bone defect filling (RBF) (%) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

The review found no eligible studies for this question.

1 finding from 1 review

Routine scale and polish every 6 months vs Routine scale and polish every 12 months

Participant satisfaction (perceived oral cleanliness) · Dentate adults without severe periodontitis, regularly attending for dental care in primary care (UK general dental practice)

It is very uncertain whether routine scale and polish every 6 months changes participant satisfaction (perceived oral cleanliness) compared with routine scale and polish every 12 months (very low certainty).

1 finding from 1 review

Autologous platelet concentrates (APC) + open flap debridement (OFD) vs Open flap debridement (access flap surgery)

Oral health-related quality of life · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

The review found no eligible studies for this question.

1 finding from 1 review

Twin Block functional appliance vs Other functional appliances (Bionator, Herbst, R-appliance, Dynamax, Bite-Jumping)

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Twin Block functional appliance showed no clear difference in final overjet compared with other functional appliances (Bionator, Herbst, R-appliance, Dynamax,… (low certainty).

1 finding from 1 review

Routine scale and polish at a fixed interval vs No scheduled scale and polish treatment

Plaque · Dentate adults without severe periodontitis, regularly attending for dental care in primary care (UK general dental practice)

Planned, regular routine scale and polish (6-monthly; 12-monthly… showed no clear difference in plaque compared with no scheduled scale and polish treatment (low certainty).

1 finding from 1 review

Electrofulguration + calcium hydroxide (CH) vs Electrofulguration + zinc oxide and eugenol (ZOE)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Electrofulguration + calcium hydroxide (CH) showed no clear difference in radiological failure compared with electrofulguration + zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review

Photodynamic therapy plus mechanical debridement vs Mechanical debridement alone

Probing pocket depth · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)

It is very uncertain whether photodynamic therapy plus mechanical debridement changes probing pocket depth (mm) compared with mechanical debridement alone (very low certainty).

1 finding from 1 review

GTR rm associated with bone substitutes + CAF vs SCTG + CAF

Aesthetic condition change related to patient's opinion · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)
1 finding from 1 review

18% CP paint-on gel (4x/day) vs 18% CP paint-on gel

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 18% CP paint-on gel (4x/day) changes tooth whitening - assessed by the dentist compared with 18% CP paint-on gel (2x/day) (very low certainty).

1 finding from 1 review