Search

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

2,543 questions · 2,589 findings · 168 reviews · Schizophrenia

No studies found 601 · 23.2%GRADE not reported 446 · 17.2%Very low 721 · 27.8%Low 505 · 19.5%Moderate 274 · 10.6%High 42 · 1.6%

HIGH DOSE (greater than or equal to 10 mg/day) vs ANY DOSE ‐ short term

Adverse effects: 5a. Movement disorders ‐ specific symptoms ‐ EPS: unspecified ‐ versus standard‐higher dose (greater than or equal to 6‐<10 mg/day) · patients with schizophrenia

HIGH DOSE (greater than or equal to 10 mg/day) probably leads to higher adverse effects: EPS: unspecified ‐ when compared with… compared with ANY DOSE ‐ short term (moderate certainty).

1 finding from 1 review

HIGH DOSE (greater than or equal to 10 mg/day) vs ANY DOSE ‐ short term

Adverse effects: 6. Movement disorders ‐ specific symptoms ‐ EPS: unspecified ‐ versus low dose (greater than or equal to 2‐<4 mg/day) · patients with schizophrenia

HIGH DOSE (greater than or equal to 10 mg/day) probably leads to higher adverse effects: EPS: unspecified ‐ when compared with low dose… compared with ANY DOSE ‐ short term (moderate certainty).

1 finding from 1 review

LOW DOSE (greater than or equal to 2‐<4 mg/day) vs ANY DOSE ‐ short term

Leaving the study early · patients with schizophrenia

LOW DOSE (greater than or equal to 2‐<4 mg/day) showed no clear difference in leaving the study early: any reason ‐ when compared with… compared with ANY DOSE ‐ short term (moderate certainty).

2 findings from 1 review

Intervention not reported

Mental state: 1a. Overall no clinically important improvement (BPRS) ‐ short term 25‐30% change BPRS1,2 ( · people with schizophrenia

The intervention showed no clear difference in mental state: 1a. Overall no clinically important improvement (BPRS)… (low certainty).

1 finding from 1 review

Intervention not reported

Mental state: 1a. Overall no clinically important improvement (BPRS) ‐ medium term 25‐30% change BPRS1,2 ( · people with schizophrenia

The intervention may leads to lower mental state: 1a. Overall no clinically important improvement (BPRS)… (low certainty).

1 finding from 1 review

INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY vs medication

Global impression: 1. Not able to be discharged (long term) · patients with schizophrenia and severe mental illness

INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY may leads to higher global impression: 1. Not able to be discharged (long term) compared with MEDICATION (low certainty).

1 finding from 1 review

INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY vs medication

Global impression: 2. Given medication during 12 months to three years · patients with schizophrenia and severe mental illness

INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY may leads to lower global impression: 2. Given medication during 12 months to three years compared with MEDICATION (low certainty).

2 findings from 1 review

PROMPT TYPE vs NO PROMPT

Did not attend appointment ‐ combination of telephone and text‐based prompts · people with severe mental disorders

It is very uncertain whether PROMPT TYPE changes did not attend appointment ‐ combination of telephone and text‐based… compared with NO PROMPT (very low certainty).

1 finding from 1 review

TEXT LETTER PROMPT vs TEXT ORIENTATION STATEMENT

Did not attend appointment ‐ any time before appointment · people with severe mental disorders

It is very uncertain whether TEXT LETTER PROMPT changes did not attend appointment ‐ any time before appointment compared with TEXT ORIENTATION STATEMENT (very low certainty).

1 finding from 1 review