Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,454 questions · 3,562 findings · 816 reviews · Headline outcomes only

No studies found 538 · 15.1%GRADE not reported 239 · 6.7%Very low 933 · 26.2%Low 1,041 · 29.2%Moderate 612 · 17.2%High 199 · 5.6%

Recombinant human soluble thrombomodulin vs heparin

Mortality from any cause (15‐day and 30‐day in‐hospital) · DIC

It is very uncertain whether recombinant human soluble thrombomodulin changes mortality from any cause (15‐day and 30‐day in‐hospital) compared with heparin (very low certainty).

1 finding from 1 review

Intervention not reported

Surgical site infection within 30 days in trials with low risk of bias (14 days to 30 days) · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery

The intervention showed no clear difference in surgical site infection within 30 days in trials with low risk of… (low certainty).

1 finding from 1 review