Cochrane · systematic review · CD008875

Post‐pyloric versus gastric tube feeding for preventing pneumonia and improving nutritional outcomes in critically ill adults

Alkhawaja, S, Martin, C, Butler, RJ, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Emergency and Critical CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 3 · 42.9%Moderate 3 · 42.9%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Post‐pyloric tube feeding compared with gastric tube feeding for critically ill adult patients

Population: critically ill adult patients
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pneumonia (
Post‐pyloric tube feeding vs gastric tube feeding
RR 0.65 [0.51, 0.84]9 studies · 819 participantsModerate
Downgraded: risk of bias
Mortality (
Post‐pyloric tube feeding vs gastric tube feeding
RR 1.03 [0.83, 1.29]11 studies · 977 participantsModerate
Downgraded: risk of bias
Percentage of total nutrition delivered to participant (
Post‐pyloric tube feeding vs gastric tube feeding
no estimate extracted7 studies · 692 participantsLow
Downgraded: risk of bias, inconsistency
Time required to achieve full nutritional target (in hours) (
Post‐pyloric tube feeding vs gastric tube feeding
no estimate extracted5 studies · 432 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Duration of mechanical ventilation in days (
Post‐pyloric tube feeding vs gastric tube feeding
no estimate extracted5 studies · 549 participantsModerate
Downgraded: risk of bias
Complications related to tube insertion (
Post‐pyloric tube feeding vs gastric tube feeding
RR 0.51 [0.19, 1.36]4 studies · 324 participantsLow
Downgraded: risk of bias, imprecision
Complications related to tube maintenance (
Post‐pyloric tube feeding vs gastric tube feeding
RR 1.63 [0.93, 2.86]7 studies · 638 participantsLow
Downgraded: risk of bias, inconsistency