Serious adverse events · adults with primary (essential) hypertension whose systolic or diastolic (or both) blood pressure levels were 130/80 mmHg or greater
It is very uncertain whether evening changes serious adverse events compared with morning dosing regimen (very low certainty).
1 finding from 1 review
Overall adverse events · adults with primary (essential) hypertension whose systolic or diastolic (or both) blood pressure levels were 130/80 mmHg or greater
It is very uncertain whether evening changes overall adverse events compared with morning dosing regimen (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · adults with primary (essential) hypertension whose systolic or diastolic (or both) blood pressure levels were 130/80 mmHg or greater
It is very uncertain whether evening changes withdrawals from treatment due to adverse events compared with morning dosing regimen (very low certainty).
1 finding from 1 review
Pain with dilation (10 mL 2% lidocaine)a,b · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an early pregnancy loss)
1 finding from 1 review
Pain with dilation (20 mL 1% lidocaine)d,e · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an early pregnancy loss)
1 finding from 1 review
Pain with aspiration (lidocaine)a,b · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an early pregnancy loss)
1 finding from 1 review
Pain with aspiration (20 mL 1% lidocaine)d,e · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an early pregnancy loss)
1 finding from 1 review
Risk for at least one adverse event per patient · patients with chronic kidney disease (CKD) pruritus
It is very uncertain whether summary of findings table ‐ Gabapentin changes risk for at least one adverse event per patient compared with pregabalin (very low certainty).
1 finding from 1 review
Pruritus · patients with chronic kidney disease (CKD) pruritus
1 finding from 1 review
Quality of life ‐ not reported · patients with chronic kidney disease (CKD) pruritus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient satisfaction ‐ not reported · patients with chronic kidney disease (CKD) pruritus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mortality before hospital discharge · preterm infants with respiratory distress for initial respiratory support
It is very uncertain whether nHFV changes mortality before hospital discharge compared with invasive respiratory therapy (very low certainty).
1 finding from 1 review
Death or chronic lung disease · newborn (term* and preterm) infants with respiratory distress for initial respiratory support
nHFV showed no clear difference in death or chronic lung disease compared with nCPAP used (low certainty).
1 finding from 1 review
Intraventricular haemorrhage, Papile grade 3/4 · newborn (term* and preterm) infants with respiratory distress for initial respiratory support
nHFV showed no clear difference in intraventricular haemorrhage, Papile grade 3/4 compared with nCPAP used (low certainty).
1 finding from 1 review
Neurodevelopmental disability · newborn (term* and preterm) infants with respiratory distress for initial respiratory support
1 finding from 1 review
Mortality before hospital discharge · preterm infants with respiratory distress for initial respiratory support
nHFV showed no clear difference in mortality before hospital discharge compared with nIPPV used (low certainty).
1 finding from 1 review
Endotracheal intubation To discharge · preterm infants with respiratory distress for initial respiratory support
nHFV showed no clear difference in endotracheal intubation To discharge compared with nIPPV used (low certainty).
1 finding from 1 review
Chronic lung disease · preterm infants with respiratory distress for initial respiratory support
nHFV may leads to lower chronic lung disease compared with nIPPV used (low certainty).
1 finding from 1 review
Death or chronic lung disease · preterm infants with respiratory distress for initial respiratory support
1 finding from 1 review
Intraventricular haemorrhage, Papile grade 3/4 · preterm infants with respiratory distress for initial respiratory support
1 finding from 1 review