Smoking cessation · people who smoke
Higher‐dose showed no clear difference in smoking cessation ‐ 42/44 mg versus 21/22 mg (24‐hour patches) compared with lower‐dose nicotine patch (moderate certainty).
3 findings from 1 review
RR 1.09 [0.93, 1.29]
5 studies · 1655 participants
Moderate
RR 1.19 [1, 1.41]
3 studies · 3446 participants
Moderate
RR 1.48 [1.06, 2.08]
1 study · 537 participants
Moderate
SAEs · people who smoke
Higher‐dose showed no clear difference in overall SAEs ‐ 42/44 mg versus 21/22 mg (24 hr patches) compared with lower‐dose nicotine patch (low certainty).
2 findings from 1 review
Treatment withdrawal · people who smoke
Higher‐dose may leads to higher treatment withdrawals ‐ 42/44 mg versus 21/22 mg (24‐hour patches) compared with lower‐dose nicotine patch (low certainty).
1 finding from 1 review
Treatment withdrawals ‐ 21 mg versus 14 mg (24‐hour patches) · people who smoke
Higher‐dose showed no clear difference in treatment withdrawals ‐ 21 mg versus 14 mg (24‐hour patches) compared with lower‐dose nicotine patch (low certainty).
1 finding from 1 review
Functional ability · people with mild‐to‐moderate dementia (at medium‐term follow‐up)
1 finding from 1 review
Self‐efficacy · people with mild‐to‐moderate dementia (at medium‐term follow‐up)
1 finding from 1 review
Mood: depression (participant self‐report) · people with mild‐to‐moderate dementia (at medium‐term follow‐up)
1 finding from 1 review
QoL · people with mild‐to‐moderate dementia (at medium‐term follow‐up)
1 finding from 1 review
Quality of life: psychological (care partner self‐report) · people with mild‐to‐moderate dementia (at medium‐term follow‐up)
1 finding from 1 review
Functional ability in targeted activities: personal goals ‐ performance (participant self‐report) · people with mild‐to‐moderate dementia (at medium‐term follow‐up)
1 finding from 1 review
Functional ability in targeted activities: personal goals ‐ performance (informant report of participant) · people with mild‐to‐moderate dementia (at medium‐term follow‐up)
1 finding from 1 review
Functional disability (Higher scores indicate higher levels of disability) · chronic pain (excluding headache) in adults
1 finding from 1 review
Quality of life (Higher scores indicate improvement) · chronic pain (excluding headache) in adults
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · chronic pain (excluding headache) in adults
1 finding from 1 review
Participant‐reported pain relief of 30% or greater · chronic pain (excluding headache) in adults
1 finding from 1 review
Pain intensity (number of people with ≥ 50% improvement) · chronic pain (excluding headache) in adults
1 finding from 1 review
Functional disability at 3 months ‐ not measured · chronic pain (excluding headache) in adults
1 finding from 1 review
Quality of life (Higher scores indicate improvement) · chronic pain (excluding headache) in adults
1 finding from 1 review
Adverse events · chronic pain (excluding headache) in adults
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · chronic pain (excluding headache) in adults
1 finding from 1 review