What do systematic reviews say?

Vitamin K antagonists vs placebo

Vitamin K antagonists showed no clear difference in symptomatic PE Treatment duration 28 ‐ 42 days compared with placebo (moderate certainty).

• Anticoagulants (extended duration) for prevention of venous thromboembolism following total hip or knee replacement or… 2016 · Cochrane Headline outcomes only
  OR 0.32 [0.01, 7.84]
  1 study · 360 participants
  Moderate

Patching vs no patching

Patching showed no clear difference in days to complete healing compared with no patching (moderate certainty).

• Patching for corneal abrasion 2016 · Cochrane Headline outcomes only
  MD 0.14 [0, 0.27]
  6 studies · 642 participants
  Moderate

Epidural pain relief vs systemic opioid‐based pain relief

Epidural pain relief showed no clear difference in mortality in hospital or up to 30 days compared with systemic opioid‐based pain relief (low certainty).

• Epidural pain relief versus systemic opioid‐based pain relief for abdominal aortic surgery 2016 · Cochrane Headline outcomes only
  RR 1.06 [0.6, 1.86]
  14 studies · 1383 participants
  Low

Epidural pain relief vs systemic opioid‐based pain relief

• Epidural pain relief versus systemic opioid‐based pain relief for abdominal aortic surgery 2016 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 162 participants
  High

Intervention not reported

• Cup feeding versus other forms of supplemental enteral feeding for newborn infants unable to fully breastfeed 2016 · Cochrane Headline outcomes only
  no estimate extracted
  522 participants
  Low

Intervention not reported

• Cup feeding versus other forms of supplemental enteral feeding for newborn infants unable to fully breastfeed 2016 · Cochrane Headline outcomes only
  no estimate extracted
  823 participants
  Low

Intervention not reported

It is very uncertain whether the intervention changes ventilator days (very low certainty).

• Nutritional support for critically ill children 2016 · Cochrane Headline outcomes only
  MD 2
  1 study · 72 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes length of stay (days) (very low certainty).

• Nutritional support for critically ill children 2016 · Cochrane Headline outcomes only
  MD 0
  1 study · 72 participants
  Very low

Responsive vs scheduled feeding

• Responsive versus scheduled feeding for preterm infants 2016 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 305 participants
  Low

Intervention not reported

It is very uncertain whether the intervention changes cannabis use quantity per day at short‐term (very low certainty).

• Psychosocial interventions for cannabis use disorder 2016 · Cochrane Headline outcomes only
  SMD 3.55 [2.51, 4.59]
  8 studies · 1600 participants
  Very low

Intervention not reported

The review found no eligible studies for this question.

• Granulocyte transfusions for treating infections in people with neutropenia or neutrophil dysfunction 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The intervention showed no clear difference in diarrhoea on day 7 (low certainty).

• Oral zinc for treating diarrhoea in children 2016 · Cochrane Headline outcomes only
  RR 0.52 [0.27, 1.02]
  2 studies · 221 participants
  Low

Intervention not reported

The intervention probably leads to lower diarrhoea on day 7 (moderate certainty).

• Oral zinc for treating diarrhoea in children 2016 · Cochrane Headline outcomes only
  RR 0.73 [0.61, 0.88]
  6 studies · 3865 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in diarrhoea on day 7 (low certainty).

• Oral zinc for treating diarrhoea in children 2016 · Cochrane Headline outcomes only
  RR 1.24 [0.99, 1.54]
  1 study · 1074 participants
  Low

Prophylactic cholinesterase inhibitor vs placebo

• Interventions for preventing delirium in hospitalised non‐ICU patients 2016 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 128 participants
  Low

Intervention not reported

• Interventions for preventing delirium in hospitalised non‐ICU patients 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 178 participants
  Very low

Intervention not reported

• Interventions for preventing delirium in hospitalised non‐ICU patients 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 68 participants
  Low

A multi‐component delirium prevention intervention vs usual care

• Interventions for preventing delirium in hospitalised non‐ICU patients 2016 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 244 participants
  Very low

Intervention not reported

• Interventions for preventing delirium in hospitalised non‐ICU patients 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 104 participants
  Moderate

Intervention not reported

• Interventions for preventing delirium in hospitalised non‐ICU patients 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 500 participants
  Moderate