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Evidence found and GRADE certainty

4,667 questions · 21,760 findings · 2,177 reviews

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No studies found 4,173 · 19.2%GRADE not reported 2,300 · 10.6%Very low 5,276 · 24.2%Low 5,764 · 26.5%Moderate 3,298 · 15.2%High 949 · 4.4%

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Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)

Full breastfeeding compared with not breastfeeding or partial breastfeeding · preterm infants

Breastfeeding with supplemental feeds by other than bottle may leads to higher full breastfeeding compared with not breastfeeding or partial… compared with breastfeeding with supplemental feeds by bottle (all trials) (low certainty).

1 finding from 1 review

Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)

Any breastfeeding (full and partial combined) compared with not breastfeeding · preterm infants

Breastfeeding with supplemental feeds by other than bottle probably leads to higher any breastfeeding (full and partial combined) compared with not… compared with breastfeeding with supplemental feeds by bottle (all trials) (moderate certainty).

1 finding from 1 review

Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)

Episodes of infection · preterm infants

Breastfeeding with supplemental feeds by other than bottle showed no clear difference in episodes of infection per infant compared with breastfeeding with supplemental feeds by bottle (all trials) (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Nausea · preventing nausea and vomiting

It is very uncertain whether antihistamines changes nausea ‐ intraoperative compared with placebo (very low certainty).

2 findings from 1 review

Opioid antagonists vs placebo

Nausea · preventing nausea and vomiting
2 findings from 1 review

Ginger vs placebo

Nausea · preventing nausea and vomiting

It is very uncertain whether ginger changes nausea ‐ intraoperative compared with placebo (very low certainty).

2 findings from 1 review

Postoperative systemic antibiotics (phenoxymethylpenicillin/penicillin VK, 7-day course), partial or total chemo-mechanical debridement and analgesics vs Matched placebo, partial or total chemo-mechanical debridement and analgesics

Number of ibuprofen tablets required · Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or systemic involvement)

Postoperative systemic antibiotics… showed no clear difference in number of ibuprofen tablets required compared with matched placebo, partial or total chemo-mechanical debridement and…; GRADE not reported.

1 finding from 1 review

Postoperative systemic antibiotics (phenoxymethylpenicillin/penicillin VK, 7-day course), partial or total chemo-mechanical debridement and analgesics vs Matched placebo, partial or total chemo-mechanical debridement and analgesics

Percussion pain at 24 hours · Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or systemic involvement)

Postoperative systemic antibiotics… showed no clear difference in percussion pain at 24 hours compared with matched placebo, partial or total chemo-mechanical debridement and…; GRADE not reported.

2 findings from 1 review