Antihistamines vs placebo: Nausea
It is very uncertain whether antihistamines changes nausea ‐ intraoperative compared with placebo (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Antihistamines vs placebo Nausea ‐ intraoperative · preventing nausea and vomiting It is very uncertain whether antihistamines changes nausea ‐ intraoperative compared with placebo (very low certainty). Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean… (2021) · Cochrane Headline outcomes only | RR 0.99 [0.47, 2.11] | 1 study · 149 participants | Very low |
Antihistamines vs placebo Nausea ‐ postoperative · preventing nausea and vomiting Antihistamines may leads to lower nausea ‐ postoperative compared with placebo (low certainty). Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean… (2021) · Cochrane Headline outcomes only | RR 0.44 [0.3, 0.64] | 4 studies · 514 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.