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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,518 questions in 135 reviews · Infectious Diseases

current versions
No studies 135 · 8.9%Ungraded 150 · 9.9%Very low 350 · 23.1%Low 420 · 27.7%Moderate 321 · 21.1%High 142 · 9.4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
A single dose of deworming drugs vs placebo
Physical fitness · public health programmes to regularly treat all children aged 16 years or less
Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas (2019) · Cochrane
no estimate extracted3 studies · 280 participantsVery low
A single dose of deworming drugs vs placebo
School attendance · public health programmes to regularly treat all children aged 16 years or less
Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas (2019) · Cochrane
no estimate extracted1 study · 304 participantsLow
A single dose of deworming drugs vs placebo
School performance · public health programmes to regularly treat all children aged 16 years or less
Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas (2019) · Cochrane
no estimate extracted1 study · 304 participantsLow
A single dose of deworming drugs vs placebo
Mortality · public health programmes to regularly treat all children aged 16 years or less
Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas (2019) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Multiple doses of deworming drugs vs placebo
Height (cm) · public health programmes to regularly treat all children aged 16 years or less
Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas (2019) · Cochrane
no estimate extracted13 studies · 13700 participantsModerate
Multiple doses of deworming drugs vs placebo
Haemoglobin (g/dL) · public health programmes to regularly treat all children aged 16 years or less
Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas (2019) · Cochrane
no estimate extracted9 studies · 5498 participantsModerate
Multiple doses of deworming drugs vs placebo
Formal tests of cognition · public health programmes to regularly treat all children aged 16 years or less
Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas (2019) · Cochrane
no estimate extracted8 studies · 35394 participantsModerate
Multiple doses of deworming drugs vs placebo
Physical fitness ‐ not measured · public health programmes to regularly treat all children aged 16 years or less
Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas (2019) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Multiple doses of deworming drugs vs placebo
School attendance · public health programmes to regularly treat all children aged 16 years or less
Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas (2019) · Cochrane
no estimate extracted3 studies · 20650 participantsVery low
Multiple doses of deworming drugs vs placebo
School performance · public health programmes to regularly treat all children aged 16 years or less
Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas (2019) · Cochrane
no estimate extracted4 studies · 34967 participantsModerate
Multiple doses of deworming drugs vs placebo
Mortality (between ages 1 and 6 years) · public health programmes to regularly treat all children aged 16 years or less
Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas (2019) · Cochrane
RR 0.95 [0.89, 1.92]3 studies · 1005135 participantsLow
A single dose of deworming drugs vs placebo
Weight (kg) · public health programmes to regularly treat all children aged 16 years or less
Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas (2019) · Cochrane
no estimate extracted14 studies · 4970 participantsVery low
Intervention NR
Microfilaraemia (mf) prevalence · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
RR 0.95 [0.85, 1.07]12 studies · 5027 participantsHigh
Intervention NR
Mf density · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extracted2 studies · 169 participantsVery low
Intervention NR
Antigenaemia prevalence · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
RR 1.07 [0.91, 1.25]2 studies · 1054 participantsHigh
Intervention NR
Antigen density · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extracted2 studies · 371 participantsVery low
Intervention NR
Adult worm prevalence detected by ultrasound ‐ not measured · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
RR 0.95 [0.61, 1.48]2 studies · 678 participantsModerate
Intervention NR
Microfilaraemia (mf) prevalence · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
RR 0.9 [0.75, 1.09]7 studies · 1102 participantsModerate
Intervention NR
Mf density · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extracted6 studies · 559 participantsVery low
Intervention NR
Mf density · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extracted6 studies · 535 participantsLow
Intervention NR
Antigenaemia prevalence · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
RR 1.03 [0.92, 1.14]5 studies · 954 participantsHigh
Intervention NR
Antigen density · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extracted3 studies · 270 participantsVery low
Intervention NR
Mf density · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extracted10 studies · 1216 participantsVery low
Intervention NR
Adult worm prevalence detected by ultrasound · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
RR 1.16 [0.72, 1.86]3 studies · 165 participantsLow
Intervention NR
Adverse events · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
RR 0.94 [0.79, 1.11]4 studies · 1589 participantsHigh
Intervention NR
Microfilaraemia (mf) prevalence · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
RR 0.84 [0.54, 1.31]4 studies · 2519 participantsModerate
Intervention NR
Mf density · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extracted3 studies · 372 participantsVery low
Intervention NR
Mf density · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extracted2 studies · 348 participantsLow
Intervention NR
Antigenaemia prevalence · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
RR 1.04 [0.94, 1.16]2 studies · 1766 participantsHigh
Intervention NR
Antigen density · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extracted2 studies · 733 participantsLow
Intervention NR
Adult worm prevalence detected by ultrasound ‐ not measured · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
RR 1.16 [0.77, 1.74]1 study · 627 participantsModerate
Intervention NR
Mf density · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extracted9 studies · 1052 participantsVery low
Intervention NR
Antigenaemia prevalence · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
RR 1.04 [0.97, 1.12]7 studies · 3774 participantsHigh
Intervention NR
Antigen density · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extracted5 studies · 1374 participantsVery low
Intervention NR
Adult worm prevalence detected by ultrasound · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
RR 1.16 [0.72, 1.86]3 studies · 165 participantsLow
Intervention NR
Adverse events · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
RR 0.97 [0.84, 1.13]6 studies · 2894 participantsHigh
Intervention NR
Microfilaraemia (mf) prevalence · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
RR 0.98 [0.81, 1.19]4 studies · 1406 participantsHigh
Intervention NR
Mf density · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extracted4 studies · 285 participantsVery low
Intervention NR
Clinical failure · adults and children with amoebic colitis
Antiamoebic drugs for treating amoebic colitis (2019) · Cochrane
RR 0.17 [0.02, 1.3]2 studies · 285 participantsLow
Intervention NR
Parasitological failure Method: stool microscopy demonstrating E histolytica cysts or trophozoites · adults and children with amoebic colitis
Antiamoebic drugs for treating amoebic colitis (2019) · Cochrane
RR 1.01 [0.58, 1.74]2 studies · 285 participantsLow
Intervention NR
Adverse events · adults and children with amoebic colitis
Antiamoebic drugs for treating amoebic colitis (2019) · Cochrane
RR 0.65 [0.46, 0.92]8 studies · 477 participantsModerate
Intervention NR
Clinical failure 1 to 14 days after end of treatment · adults and children with amoebic colitis
Antiamoebic drugs for treating amoebic colitis (2019) · Cochrane
RR 0.33 [0.11, 0.98]3 studies · 1025 participantsVery low
Intervention NR
Parasitological failure 1 to 14 days after end of treatment Method: stool microscopy demonstrating E histolytica cysts or trophozoites · adults and children with amoebic colitis
Antiamoebic drugs for treating amoebic colitis (2019) · Cochrane
RR 0.36 [0.15, 0.86]3 studies · 720 participantsLow
Intervention NR
Adverse events · adults and children with amoebic colitis
Antiamoebic drugs for treating amoebic colitis (2019) · Cochrane
no estimate extracted3 studies · 1025 participantsVery low
Intervention NR
Failure of rehydration · acute diarrhoea in children
Racecadotril for acute diarrhoea in children (2019) · Cochrane
RR 0.41 [0.13, 1.23]2 studies · 192 participantsLow
Intervention NR
Duration of diarrhoea · acute diarrhoea in children
Racecadotril for acute diarrhoea in children (2019) · Cochrane
no estimate extracted5 studies · 867 participantsVery low
Intervention NR
Number of stools: measured in the first 24 hours after introduction of racecadotril · acute diarrhoea in children
Racecadotril for acute diarrhoea in children (2019) · Cochrane
no estimate extracted2 studies · 258 participantsVery low
Intervention NR
Stool output: measured in the first 48 hours after introduction of racecadotril · acute diarrhoea in children
Racecadotril for acute diarrhoea in children (2019) · Cochrane
no estimate extracted2 studies · 301 participantsLow