Cochrane · systematic review · CD009359
Racecadotril for acute diarrhoea in children
Liang, Y, Zhang, L, Zeng, L, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 33.3%Low 4 · 66.7%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings table 1
Population: acute diarrhoea in children
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Failure of rehydration | RR 0.41 [0.13, 1.23] | 2 studies · 192 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Duration of diarrhoea | no estimate extracted | 5 studies · 867 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Number of stools: measured in the first 24 hours after introduction of racecadotril | no estimate extracted | 2 studies · 258 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Stool output: measured in the first 48 hours after introduction of racecadotril | no estimate extracted | 2 studies · 301 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Length of hospital stay for inpatients | no estimate extracted | 2 studies · 224 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Adverse events: number of all types of adverse events | RR 0.9 [0.66, 1.22] | 5 studies · 688 participants | Low Downgraded: risk of bias, imprecision, inconsistency |