Hypertonic saline 7% vs hypertonic saline
FEV1 % predicted: relative change from baseline · children with cystic fibrosis
1 finding from 1 review
- no estimate extracted1 study · 30 participantsVery low
Findings
What do systematic reviews say?
1,788 questions · 1,849 findings · 336 reviews
No studies found 245 · 13.3%GRADE not reported 126 · 6.8%Very low 612 · 33.1%Low 512 · 27.7%Moderate 305 · 16.5%High 49 · 2.7%
Hypertonic saline 3% to 7% vs Normal saline
FEV1 % predicted: relative change from baseline · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
1 finding from 1 review
- no estimate extracted1 study · 130 participantsLow
Laparoscopic hysterectomy vs abdominal hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
Laparoscopic hysterectomy showed no clear difference in major short‐term complications (dichotomous) compared with abdominal hysterectomy (low certainty).
1 finding from 1 review
- Surgical approach to hysterectomy for benign gynaecological disease 2023 · Cochrane Headline outcomes onlyOR 1.43 [0.67, 3.04]9 studies · 852 participantsLow
Laparoscopic hysterectomy vs vaginal hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
Laparoscopic hysterectomy showed no clear difference in major short‐term complications (dichotomous) compared with vaginal hysterectomy (low certainty).
1 finding from 1 review
- Surgical approach to hysterectomy for benign gynaecological disease 2023 · Cochrane Headline outcomes onlyOR 0.98 [0.22, 4.39]4 studies · 276 participantsLow
Robotic hysterectomy vs laparoscopic hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
The review found no eligible studies for this question.
1 finding from 1 review
- Surgical approach to hysterectomy for benign gynaecological disease 2023 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Single‐port laparoscopic hysterectomy vs laparoscopic hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
The review found no eligible studies for this question.
1 finding from 1 review
- Surgical approach to hysterectomy for benign gynaecological disease 2023 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Total laparoscopic hysterectomy vs laparoscopic‐assisted vaginal hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
It is very uncertain whether total laparoscopic hysterectomy changes major short‐term complications (dichotomous) compared with laparoscopic‐assisted vaginal hysterectomy (very low certainty).
1 finding from 1 review
- Surgical approach to hysterectomy for benign gynaecological disease 2023 · Cochrane Headline outcomes onlyOR 0.28 [0.03, 2.45]1 study · 101 participantsVery low
V‐NOTES vs laparoscopic hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
The review found no eligible studies for this question.
1 finding from 1 review
- Surgical approach to hysterectomy for benign gynaecological disease 2023 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Vaginal hysterectomy vs abdominal hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
Vaginal hysterectomy showed no clear difference in major short‐term complications (dichotomous) compared with abdominal hysterectomy (low certainty).
1 finding from 1 review
- Surgical approach to hysterectomy for benign gynaecological disease 2023 · Cochrane Headline outcomes onlyOR 3.14 [0.48, 20.55]3 studies · 216 participantsLow
Systemic aminocaproic acid vs placebo
Short‐term visual acuity 20/40 or better ≤ 2 weeks after treatment · people with traumatic hyphema
Systemic aminocaproic acid showed no clear difference in short‐term visual acuity 20/40 or better ≤ 2 weeks after treatment compared with placebo (low certainty).
1 finding from 1 review
- RR 0.87 [0.57, 1.32]1 study · 34 participantsLow
Systemic tranexamic acid vs control
Short‐term visual acuity 20/40 or better ≤ 2 weeks after treatment · people with traumatic hyphema
Systemic tranexamic acid showed no clear difference in short‐term visual acuity 20/40 or better ≤ 2 weeks after treatment compared with control (moderate certainty).
1 finding from 1 review
- RR 1.12 [1, 1.25]4 studies · 425 participantsModerate
Systemic or topical corticosteroids vs placebo or control
Short‐term visual acuity between 20/20 and 20/40 ≤ 2 weeks after treatment; oral corticosteroids · people with traumatic hyphema
Systemic or topical corticosteroids showed no clear difference in short‐term visual acuity between 20/20 and 20/40 ≤ 2 weeks after… compared with placebo or control treatment (low certainty).
1 finding from 1 review
- RR 1.2 [0.97, 1.49]2 studies · 277 participantsLow
Systemic or topical corticosteroids vs placebo or control
Short‐term visual acuity between 20/20 and 20/40 ≤ 2 weeks after treatment; topical corticosteroids · people with traumatic hyphema
It is very uncertain whether systemic or topical corticosteroids changes short‐term visual acuity between 20/20 and 20/40 ≤ 2 weeks after… compared with placebo or control treatment (very low certainty).
1 finding from 1 review
- RR 0.75 [0.38, 1.47]1 study · 34 participantsVery low
Other pharmaceutical agents vs placebo or control
Visual acuity · people with traumatic hyphema
Other pharmaceutical agents showed no clear difference in short‐term visual acuity between 20/20 and 20/60 at end of… compared with placebo or other control interventions (low certainty).
1 finding from 1 review
- RR 0.82 [0.46, 1.45]1 study · 34 participantsLow
Non‐pharmaceutical interventions vs control
Visual acuity · people with traumatic hyphema
Non‐pharmaceutical interventions showed no clear difference in short‐term visual acuity between 20/20 and 20/60 at end of… compared with control (low certainty).
2 findings from 1 review
- RR 0.82 [0.67, 1]1 study · 46 participantsLow
- RR 1.1 [0.84, 1.44]1 study · 52 participantsLow
Topical aminocaproic acid vs placebo
Short‐term visual acuity 20/40 or better ≤ 2 weeks after treatment · people with traumatic hyphema
Topical aminocaproic acid showed no clear difference in short‐term visual acuity 20/40 or better ≤ 2 weeks after treatment compared with placebo (low certainty).
1 finding from 1 review
- RR 0.87 [0.47, 1.6]1 study · 51 participantsLow
Lower salt intake vs usual or high salt intake
Systolic blood pressure · patients with diabetes with or without CKD
1 finding from 1 review
- Altered dietary salt intake for preventing diabetic kidney disease and its progression 2023 · Cochrane Headline outcomes onlyno estimate extracted5 studies · 112 participantsLow
Lower salt intake vs usual or high salt intake
Diastolic blood pressure · patients with diabetes with or without CKD
1 finding from 1 review
- Altered dietary salt intake for preventing diabetic kidney disease and its progression 2023 · Cochrane Headline outcomes onlyno estimate extracted5 studies · 112 participantsLow
Home‐based vs centre‐based cardiac rehabilitation
HRQoL Validated measures of HRQoL (e.g. Short Form Health Survey (SF‐36), Sickness Impact Profile, Nottingham Health Profile) · Patients with heart disease
1 finding from 1 review
- no estimate extracted18 studies · 2207 participantsModerate
Motivational interviewing vs assessment and feedback
Extent of substance use at short‐term · people with substance use (adults, young adults, adolescents)
1 finding from 1 review
- no estimate extracted7 studies · 854 participantsLow