Cochrane · systematic review · CD006763
Altered dietary salt intake for preventing diabetic kidney disease and its progression
Hodson, EM, Cooper, TE · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
Kidney and TransplantAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
13
current version
GRADE rated
13
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 13 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Reduced salt intake versus usual or high salt intake for preventing diabetic kidney disease and its progression
Population: patients with diabetes with or without CKD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Systolic BP: long‐term studies Duration: up to 12 weeks Reduced salt intake vs usual or high salt intake | no estimate extracted | 7 studies · 288 participants | Low Downgraded: inconsistency |
Systolic BP: short‐term studies Duration: 1 week Reduced salt intake vs usual or high salt intake | no estimate extracted | 5 studies · 112 participants | Low Downgraded: inconsistency |
Diastolic BP: long‐term studies Duration: up to 12 weeks Reduced salt intake vs usual or high salt intake | no estimate extracted | 7 studies · 288 participants | Low Downgraded: inconsistency |
Diastolic BP: short‐term studies Duration: 1 week Reduced salt intake vs usual or high salt intake | no estimate extracted | 5 studies · 112 participants | Low Downgraded: inconsistency |
MAP: all studies Duration: up to 12 weeks Reduced salt intake vs usual or high salt intake | no estimate extracted | 13 studies · 421 participants | Low Downgraded: inconsistency |
GFF: all studies Duration: up to 12 weeks Reduced salt intake vs usual or high salt intake | no estimate extracted | 12 studies · 392 participants | Low Downgraded: inconsistency |
Body weight: all studies Duration: up to 12 weeks Reduced salt intake vs usual or high salt intake | no estimate extracted | 12 studies · 454 participants | Low Downgraded: inconsistency |
Net change in blood pressure in hypertensive and normotensive participants with a reduced salt intake versus usual or high salt intake for preventing diabetic kidney disease and its progression
Population: patients with diabetes with or without CKD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Systolic BP Duration: up to 12 weeks Net change in blood pressure in hypertensive and normotensive participants with a reduced salt intake vs usual or high salt intake | no estimate extracted | 5 studies · 108 participants | Low Downgraded: inconsistency |
Diastolic BP Duration: up to 12 weeks Net change in blood pressure in hypertensive and normotensive participants with a reduced salt intake vs usual or high salt intake | no estimate extracted | 5 studies · 108 participants | Low Downgraded: inconsistency |
MAP Duration: up to 12 weeks Net change in blood pressure in hypertensive and normotensive participants with a reduced salt intake vs usual or high salt intake | no estimate extracted | 3 studies · 59 participants | Low Downgraded: inconsistency |
Net change in blood pressure in participants with type 1 or type 2 diabetes with a reduced salt diet versus usual or high salt intake for preventing diabetic kidney disease and its progression
Population: patients with diabetes with or without CKD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Systolic BP Duration: up to 12 weeks Net change in blood pressure in participants with type 1 or type 2 diabetes with a reduced salt diet vs usual or high salt intake | no estimate extracted | 4 studies · 96 participants | Low Downgraded: inconsistency |
Diastolic BP: Duration: up to 12 weeks Net change in blood pressure in participants with type 1 or type 2 diabetes with a reduced salt diet vs usual or high salt intake | no estimate extracted | 4 studies · 96 participants | Low Downgraded: inconsistency |
MAP Duration: up to 12 weeks Net change in blood pressure in participants with type 1 or type 2 diabetes with a reduced salt diet vs usual or high salt intake | no estimate extracted | 3 studies · 62 participants | Low Downgraded: inconsistency |