Antidepressants vs placebo
- Pharmacological, psychological and non‐invasive brain stimulation interventions for preventing depression after stroke 2020 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 116 participantsVery low
It is very uncertain whether pharmacological interventions (antidepressants) changes adverse events: death ‐ at end of treatment Analysis 1.12 compared with placebo (very low certainty).
Summary of findings table ‐ Psychological treatment showed no clear difference in depression remission ‐ short term compared with control (low certainty).
It is very uncertain whether summary of findings table ‐ Psychological treatment changes all‐cause mortality ‐ short‐term compared with control (very low certainty).
Summary of findings table ‐ Psychological treatment showed no clear difference in cardiovascular mortality ‐ long‐term compared with control; GRADE not reported.
The review found no eligible studies for this question.
Psychological intervention with or without other rehabilitation showed no clear difference in total mortalityDeaths compared with control (usual care/other rehabilitation) (moderate certainty).
Psychological intervention with or without other rehabilitation may leads to lower cardiac mortalityDeaths compared with control (usual care/other rehabilitation) (low certainty).
Psychological intervention with or without other rehabilitation showed no clear difference in non‐fatal MI compared with control (usual care/other rehabilitation) (low certainty).
Psychological intervention with or without other rehabilitation showed no clear difference in revascularisation (CABG and PCI combined) compared with control (usual care/other rehabilitation) (moderate certainty).