Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

256 questions · 278 findings · 34 reviews · ENT

No studies found 86 · 30.9%GRADE not reported 1 · 0.4%Very low 88 · 31.7%Low 66 · 23.7%Moderate 35 · 12.6%High 2 · 0.7%

Betahistine vs placebo

Change in tinnitus loudness measured by a visual analogue scale (range 0 to more than 10) · patients with subjective idiopathic tinnitus
1 finding from 1 review

Betahistine vs placebo

Significant adverse events · patients with subjective idiopathic tinnitus
2 findings from 1 review

Betahistine vs placebo

Change in Tinnitus Severity Index (range 0 to 56) · patients with subjective idiopathic tinnitus
1 finding from 1 review

Betahistine vs placebo

Tinnitus symptom severity · patients with subjective idiopathic tinnitus
1 finding from 1 review

Betahistine vs placebo

Depressive symptoms · patients with subjective idiopathic tinnitus

The review found no eligible studies for this question.

1 finding from 1 review
  • Betahistine for tinnitus 2018 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Betahistine vs placebo

Symptoms of generalised anxiety · patients with subjective idiopathic tinnitus

The review found no eligible studies for this question.

1 finding from 1 review
  • Betahistine for tinnitus 2018 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Antibiotics vs placebo, no treatment or therapy of unproven effectiveness

Complete resolution of OME at 2 to 3 months · Children with otitis media with effusion

Antibiotics probably leads to higher complete resolution of OME at 2 to 3 months compared with placebo, no treatment or therapy of unproven effectiveness (moderate certainty).

2 findings from 1 review

Antibiotics vs placebo, no treatment or therapy of unproven effectiveness

Complete resolution of OME at more than 6 months · Children with otitis media with effusion

Antibiotics may leads to higher complete resolution of OME at more than 6 months compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).

1 finding from 1 review

Betahistine vs placebo

Proportion of patients with improvement according to global judgement of patient subgrouped by diagnosis№ of participants: 606(11 RCTs) · patients with symptoms of vertigo

Betahistine may leads to higher proportion of patients with improvement according to global… compared with placebo (low certainty).

1 finding from 1 review

Betahistine vs placebo

Proportion of patients with adverse effects№ of participants: 819(12 RCTs) · patients with symptoms of vertigo

Betahistine showed no clear difference in proportion of patients with adverse effects№ of participants: 819(12… compared with placebo (low certainty).

1 finding from 1 review