All‐cause mortality (90‐day) · people with intermediate‐risk (submassive) APE
It is very uncertain whether ultrasound‐assisted catheter‐directed thrombolysis plus standard… changes all‐cause mortality (90‐day) compared with standard intravenous heparinisation (very low certainty).
1 finding from 1 review
Treatment‐associated major haemorrhage ( · people with intermediate‐risk (submassive) APE
1 finding from 1 review
Treatment‐associated minor haemorrhage ( · people with intermediate‐risk (submassive) APE
It is very uncertain whether ultrasound‐assisted catheter‐directed thrombolysis plus standard… changes treatment‐associated minor haemorrhage ( compared with standard intravenous heparinisation (very low certainty).
1 finding from 1 review
Recurrent APE requiring retreatment or change to a different APE treatment ( · people with intermediate‐risk (submassive) APE
1 finding from 1 review
Length of hospital stay · people with intermediate‐risk (submassive) APE
1 finding from 1 review
Quality of life  · people with intermediate‐risk (submassive) APE
1 finding from 1 review
BMD Z score (total hip/femoral neck) · children and adults with β‐thalassaemia major and low bone mass
Summary of findings – zinc probably leads to higher BMD Z score (total hip/femoral neck) compared with placebo (moderate certainty).
1 finding from 1 review
BMD Z score (lumbar spine) · children and adults with β‐thalassaemia major and low bone mass
Summary of findings – zinc probably leads to higher BMD Z score (lumbar spine) compared with placebo (moderate certainty).
1 finding from 1 review
BMD Z score (wrist) · children and adults with β‐thalassaemia major and low bone mass
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Incidence of fractures · children and adults with β‐thalassaemia major and low bone mass
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mobility · children and adults with β‐thalassaemia major and low bone mass
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · children and adults with β‐thalassaemia major and low bone mass
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects of treatment · children and adults with β‐thalassaemia major and low bone mass
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
BMD Z score (total hip/femoral neck) · adults with β‐thalassaemia and low bone mass
Summary of findings – denosumab showed no clear difference in BMD Z score (total hip/femoral neck) compared with placebo (low certainty).
1 finding from 1 review
BMD Z score (lumbar spine) · adults with β‐thalassaemia and low bone mass
Summary of findings – denosumab showed no clear difference in BMD Z score (lumbar spine) compared with placebo (low certainty).
1 finding from 1 review
BMD Z score (wrist) · adults with β‐thalassaemia and low bone mass
Summary of findings – denosumab showed no clear difference in BMD Z score (wrist) compared with placebo (low certainty).
1 finding from 1 review
Incidence of fractures · adults with β‐thalassaemia and low bone mass
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mobility · adults with β‐thalassaemia and low bone mass
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · adults with β‐thalassaemia and low bone mass
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects of treatment · adults with β‐thalassaemia and low bone mass
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found