Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

329 questions · 344 findings · 34 reviews · Gut

No studies found 31 · 9%GRADE not reported 6 · 1.7%Very low 101 · 29.4%Low 82 · 23.8%Moderate 86 · 25%High 38 · 11%

Laser therapy vs Photodynamic therapy

Dysphagia improvement (2‐point grade or more) · patients with dysphagia in oesophageal cancer

Laser showed no clear difference in dysphagia improvement (2‐point grade or more) compared with photodynamic therapy (PDT) (moderate certainty).

1 finding from 1 review

Laser therapy vs Photodynamic therapy

Adverse effects ‐ All adverse effects · patients with dysphagia in oesophageal cancer

Laser showed no clear difference in adverse effects ‐ All adverse effects compared with photodynamic therapy (PDT) (moderate certainty).

1 finding from 1 review

Any antibiotic regimen plus N‐acetylcysteine vs the same regimen without N‐acetylcysteine (with or without placebo)

Eradication rate · patients with Helicobacter pylori infection

It is very uncertain whether any antibiotic regimen plus N‐acetylcysteine changes eradication rate compared with the same regimen without N‐acetylcysteine (with or without placebo) (very low certainty).

1 finding from 1 review

Any antibiotic regimen plus N‐acetylcysteine vs the same regimen without N‐acetylcysteine (with or without placebo)

Gastrointestinal adverse events · patients with Helicobacter pylori infection

It is very uncertain whether any antibiotic regimen plus N‐acetylcysteine changes gastrointestinal adverse events compared with the same regimen without N‐acetylcysteine (with or without placebo) (very low certainty).

1 finding from 1 review

Any antibiotic regimen plus N‐acetylcysteine vs the same regimen without N‐acetylcysteine (with or without placebo)

Allergic adverse events · patients with Helicobacter pylori infection

It is very uncertain whether any antibiotic regimen plus N‐acetylcysteine changes allergic adverse events compared with the same regimen without N‐acetylcysteine (with or without placebo) (very low certainty).

1 finding from 1 review