Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

364 questions · 389 findings · 54 reviews

No studies found 95 · 24.4%GRADE not reported 40 · 10.3%Very low 45 · 11.6%Low 126 · 32.4%Moderate 76 · 19.5%High 7 · 1.8%

Lanolin vs no intervention

Nipple pain 5‐point verbal descriptor scale · breastfeeding women with sore nipples

Lanolin showed no clear difference in nipple pain 5‐point verbal descriptor scale compared with no intervention (control group) (low certainty).

3 findings from 1 review

Expressed breast milk vs no intervention

Nipple pain 5‐point verbal descriptor scale · breastfeeding women with sore nipples

Expressed breast milk showed no clear difference in nipple pain 5‐point verbal descriptor scale compared with no intervention (control group) (low certainty).

3 findings from 1 review

Bottle-feeding only vs Breastfeeding only

Early childhood caries (ECC) · Healthy children under 6 years in South Africa

No significant difference in caries odds was found between bottle-fed-only and breast-fed-only children (meta-analysis reported no difference; pooled estimate in an unavailable supplementary figure; not GRADE-rated).

1 finding from 1 review

Probiotics vs placebo

Incidence of mastitis within 6 months postpartum · postpartum breastfeeding women

Probiotics may leads to lower incidence of mastitis within 6 months postpartum compared with placebo (low certainty).

1 finding from 1 review

Antibiotics vs topical treatments

Incidence of mastitis within 6 months postpartum · postpartum breastfeeding women

Antibiotics showed no clear difference in incidence of mastitis within 6 months postpartum ‐ Antibiotics… compared with topical treatments (low certainty).

2 findings from 1 review