Clinical healing ‐ time to clinical/radiographic fracture consolidation (weeks) · adults (aged ≥ 16 years) with acute middle third clavicle fractures
It is very uncertain whether intramedullary fixation changes clinical healing ‐ time to clinical/radiographic fracture… compared with open reduction and internal fixation with plate (very low certainty).
1 finding from 1 review
Adverse events ‐ total of adverse events (various: mainly infection; cosmetic result ‐ e.g. prominent metalwork ‐ and symptomatic hardware) · adults (aged ≥ 16 years) with acute middle third clavicle fractures
It is very uncertain whether intramedullary fixation changes adverse events ‐ total of adverse events (various: mainly infection;… compared with open reduction and internal fixation with plate (very low certainty).
1 finding from 1 review
Quality of life ‐ not measured · adults (aged ≥ 16 years) with acute middle third clavicle fractures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Return to previous activities ‐ not measured · adults (aged ≥ 16 years) with acute middle third clavicle fractures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Relief of pain · participants with painful obstructive chronic pancreatitis
Endoscopy probably leads to higher pain relief ‐ middle‐term compared with surgery (moderate certainty).
2 findings from 1 review
Mortality ‐ not reported · participants with painful obstructive chronic pancreatitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life ‐ not measured · participants with painful obstructive chronic pancreatitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Endocrine pancreatic insufficiency (new onset) · participants with painful obstructive chronic pancreatitis
Surgery may leads to lower endocrine pancreatic insufficiency (new onset) compared with conservative treatment (low certainty).
1 finding from 1 review
Exocrine pancreatic insufficiency (new onset) · participants with painful obstructive chronic pancreatitis
Surgery may leads to lower exocrine pancreatic insufficiency (new onset) compared with conservative treatment (low certainty).
1 finding from 1 review
Major complications and mortality · participants with painful obstructive chronic pancreatitis
1 finding from 1 review
Quality of Life: SF‐36 (physical component) · participants with painful obstructive chronic pancreatitis
1 finding from 1 review
Health‐related quality of life (mental) · participants with painful obstructive chronic pancreatitis
1 finding from 1 review
Endocrine pancreatic insufficiency (new onset) ‐ long‐term · participants with painful obstructive chronic pancreatitis
Endoscopy showed no clear difference in endocrine pancreatic insufficiency (new onset) ‐ long‐term compared with surgery (low certainty).
1 finding from 1 review
Exocrine pancreatic insufficiency (new onset) · participants with painful obstructive chronic pancreatitis
Endoscopy showed no clear difference in exocrine pancreatic insufficiency (new onset) ‐ long‐term compared with surgery (moderate certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · participants with painful obstructive chronic pancreatitis
Surgery may leads to higher pain relief compared with conservative treatment (low certainty).
1 finding from 1 review
Major complications ‐ not reported · participants with painful obstructive chronic pancreatitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of Life: SF‐36 scale from 0 to 100 (higher scores = better outcome) · adults with tibial plateau fracture (Schatzker types V or VI)
1 finding from 1 review
Function Standardised scale with positive score indicating a better outcome. Scale from 0 (worst) to 100 (best). · adults with tibial plateau fracture (Schatzker types V or VI)
1 finding from 1 review
Physical function · adults with tibial plateau fracture (Schatzker types V or VI)
1 finding from 1 review
Adverse eventse · adults with tibial plateau fracture (Schatzker types V or VI)
It is very uncertain whether circular external fixation with limited internal fixation (hybrid… changes adverse eventse compared with standard open reduction internal fixation (very low certainty).
1 finding from 1 review