Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,345 questions · 4,525 findings · 483 reviews

No studies found 1,024 · 22.6%GRADE not reported 388 · 8.6%Very low 1,172 · 25.9%Low 1,227 · 27.1%Moderate 576 · 12.7%High 138 · 3%

Regular‐dose postoperative 5‐Fluorouracil vs control

Complications ‐ wound leak ‐ high risk of failure · participants with glaucoma surgery

Regular‐dose postoperative 5‐Fluorouracil probably leads to higher complications ‐ wound leak ‐ high risk of failure compared with control (moderate certainty).

1 finding from 1 review

Combined oral and intravenous vs oral or intravenous alone

Wound infection · colorectal surgery

Combined oral and intravenous leads to lower surgical wound infection: oral + iv versus iv alone compared with oral or intravenous alone (high certainty).

2 findings from 1 review

Artificial urinary sphincter implantation vs endourethral Macroplastique injection

Success rate ‐ dry · men with stress urinary incontinence due to presumed sphincter deficiency after prostate surgery

It is very uncertain whether artificial urinary sphincter implantation changes success rate ‐ dry compared with endourethral Macroplastique injection (very low certainty).

1 finding from 1 review