Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,006 questions · 3,171 findings · 607 reviews · Headline outcomes only

No studies found 411 · 13%GRADE not reported 153 · 4.8%Very low 968 · 30.5%Low 897 · 28.3%Moderate 589 · 18.6%High 153 · 4.8%

Intervention not reported

All‐cause mortality Median · individuals without known diabetes mellitus but at high risk for the condition

The intervention showed no clear difference in all‐cause mortality Median (low certainty).

1 finding from 1 review

Intervention not reported

Diabetes‐related mortality Assessed according to whether diabetes was included anywhere on the death certificate · individuals without known diabetes mellitus but at high risk for the condition

The intervention showed no clear difference in diabetes‐related mortality Assessed according to whether diabetes… (low certainty).

1 finding from 1 review

Intervention not reported

Diabetes‐related morbidity · individuals without known diabetes mellitus but at high risk for the condition

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Incidence of type 2 diabetes · individuals without known diabetes mellitus but at high risk for the condition

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Health‐related quality of life · individuals without known diabetes mellitus but at high risk for the condition

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events · individuals without known diabetes mellitus but at high risk for the condition

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Socioeconomic effects · individuals without known diabetes mellitus but at high risk for the condition

The review found no eligible studies for this question.

1 finding from 1 review

Titrated oxygen therapy vs high‐flow oxygen therapy

Mortality (respiratory‐ related and all‐cause · adults with acute exacerbations of chronic obstructive pulmonary disease

Titrated oxygen therapy may leads to lower mortality (respiratory‐ related and all‐cause compared with high‐flow oxygen therapy (low certainty).

1 finding from 1 review

Titrated oxygen therapy vs high‐flow oxygen therapy

Ventilation of any type · adults with acute exacerbations of chronic obstructive pulmonary disease

Titrated oxygen therapy showed no clear difference in ventilation of any type compared with high‐flow oxygen therapy (low certainty).

1 finding from 1 review