Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,511 questions · 2,668 findings · 290 reviews

No studies found 743 · 27.8%GRADE not reported 329 · 12.3%Very low 775 · 29%Low 484 · 18.1%Moderate 279 · 10.5%High 58 · 2.2%

Intervention not reported

Oswestry Disability Index ‐ 6 weeks · lumbar spinal stenosis

The intervention showed no clear difference in oswestry Disability Index ‐ 6 weeks (low certainty).

1 finding from 1 review

Intervention not reported

Visual Analogue Scale (VAS) ‐ 6 weeks · lumbar spinal stenosis

The intervention showed no clear difference in visual Analogue Scale (VAS) ‐ 6 weeks (low certainty).

1 finding from 1 review

Intervention not reported

Zurich Claudication Questionnaire ‐ 6 weeks · lumbar spinal stenosis

The intervention showed no clear difference in zurich Claudication Questionnaire ‐ 6 weeks (low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Function (all scores/instruments): intermediate term IKDC 2000 (version) score. Scale from: 0 to 100; higher scores = better function. · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes function (all scores/instruments): intermediate term IKDC 2000… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Function (all scores/instruments): long term Scale from: 0 to 100; higher scores = better function. · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes function (all scores/instruments): long term Scale from: 0 to 100;… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

QoL · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes quality of life: long‐term KOOS QOL score. Scale 0 to 100; higher… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Failure of treatment and adverse effects: long‐term Participants with surgery and symptom recurrence · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes failure of treatment and adverse effects: long‐term Participants… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Pain North Americal Spine Society pain scores. Scale from: 0 to 100 (higher scores indicate less pain). · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes pain: long‐term KOOS Pain score. Scale 0 to 100; higher scores =… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Activity · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes activity: intermediate term (1 to 5 years compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Activity: long term (5 or more years · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes activity: long term (5 or more years compared with microfracture (very low certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Recanalisation or persistence of reflux at 6 weeks · people requiring intervention for short saphenous vein varices

Endovenous laser ablation probably leads to lower recanalisation or persistence of reflux at 6 weeks compared with conventional surgery (moderate certainty).

1 finding from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Disease‐specific quality of life · people requiring intervention for short saphenous vein varices
2 findings from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Recurrence of reflux at 1 year · people requiring intervention for short saphenous vein varices

Endovenous laser ablation may leads to lower recurrence of reflux at 1 year compared with conventional surgery (low certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Recurrence · people requiring intervention for short saphenous vein varices

Endovenous laser ablation showed no clear difference in clinical evidence of recurrence after 1 year compared with conventional surgery (low certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Disease‐specific quality of life · people requiring intervention for short saphenous vein varices
2 findings from 1 review