Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Fibrin glue instillation under skin flaps vs no‐fibrin

PostoperativecomplicationsRR · people with breast and axillary surgery

Fibrin glue instillation under skin flaps showed no clear difference in postoperativecomplicationsRR compared with no‐fibrin (low certainty).

1 finding from 1 review

Interferon + chemotherapy vs chemotherapy alone

Adverse event (flu‐like symptoms) · Women with advanced (Stage II‐IV) epithelial ovarian cancer who have undergone surgery

Interferon + chemotherapy showed no clear difference in adverse event (flu‐like symptoms) compared with chemotherapy alone (low certainty).

1 finding from 1 review

Perioperative statins vs placebo or no treatment

All cardiovascular death · participants with improving outcomes during and after noncardiac vascular surgery.

Perioperative statins showed no clear difference in death from cardiovascular causes compared with placebo or no treatment (low certainty).

1 finding from 1 review

Perioperative statins vs placebo or no treatment

Non‐fatal MI · participants with improving outcomes during and after noncardiac vascular surgery.

Perioperative statins showed no clear difference in myocardial infarction (non‐fatal) compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Intervention not reported

Surgical failure (intraocular pressure >21mmHg) ( · patients with glaucoma surgery

The intervention probably leads to lower surgical failure (intraocular pressure >21mmHg) ( (moderate certainty).

1 finding from 1 review

Intervention not reported

Intraocular pressure ( · patients with glaucoma surgery
1 finding from 1 review