Question · asked by 1 review

Interferon vs observation: Progression‐free survival

Interferon showed no clear difference in progression‐free survival compared with observation alone (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Interferon vs observation alone
Progression‐free survival · women with advanced (Stage II‐IV) epithelial ovarian cancer who have undergone surgery
Interferon showed no clear difference in progression‐free survival compared with observation alone (low certainty).
Interferon after surgery for women with advanced (Stage II‐IV) epithelial ovarian cancer (2013) · Cochrane Headline outcomes only
HR 0.99 [0.79, 1.24]2 studies · 370 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interferon after surgery for women with advanced (Stage II‐IV) epithelial ovarian cancer
2013 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.