DMFT/DMFS index (dental caries experience) · Children aged 0-12 years in Ireland
The single Irish study showed lower DMFT/S with OHPP (OR 0.52, 95% CI 0.45 to 0.61; ungraded, single study).
1 finding from 1 review
Root carious lesions prevention · Older adults with root carious lesions (exposed root surfaces)
38% silver diamine fluoride reduced root-caries increment (DMFRS/DFRS) versus placebo, MD −0.33 (95% CI −0.39 to −0.28) (ungraded).
3 findings from 1 review
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
MTA and calcium hydroxide had similar clinical and radiographic pulpotomy success at 6 months (RR 1.00, 95% CI 0.94 to 1.06; 2 RCTs; ungraded).
2 findings from 1 review
Care index (CI), permanent teeth · Children aged 1-18 years
The care index (met dental care need) for permanent teeth could not be meta-analyzed because no study reported variance; it was lower or equal in children with learning disabilities in 5 of 8 studies (certainty not graded).
1 finding from 1 review
Arrest or reversal of noncavitated approximal carious lesions · Children and adults with noncavitated carious lesions on approximal surfaces (primary and permanent teeth)
5% NaF varnish may not differ from Resin infiltration for arrest or reversal of approximal carious lesions (RR 1.09, 95% CI 0.32 to 3.65; very low certainty).
1 finding from 1 review
DMFT/DMFS index (dental caries experience) · Children aged 0-12 years in Japan
The single Japanese study yielded a degenerate estimate of OR 0.00 (95% CI 0.00 to 0.00; ungraded, single study).
1 finding from 1 review
Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth)
12% SDF solution (applied annually) did not differ from 12% SDF solution (applied biannually) for arrest or reversal of cavitated coronal carious lesions (RR 0.94, 95% CI 0.87 to 1.02; high certainty).
4 findings from 1 review
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Arrest or reversal of noncavitated facial/lingual carious lesions · Children and adults with noncavitated carious lesions on facial/lingual surfaces (primary and permanent teeth)
10% CPP-ACP cream (+ 900-ppm NaF mouthrinse + 1,000-ppm NaF dentifrice) may not differ from Placebo cream (+ 900-ppm NaF mouthrinse + 1,000-ppm NaF dentifrice) for arrest or reversal of facial/lingual carious lesions (RR 1.28, 95% CI 0.97 to 1.68; low certainty).
3 findings from 1 review
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
A single RCT found no difference in pulpotomy success between MTA and calcium-enriched mixture (both 100% at 6 and 12 months; not pooled; ungraded).
1 finding from 1 review
Single RCT (Nosrat 2012, 118 roots): 100% clinical and radiographic success in both MTA and CEM at 6 and 12 months (MTA 53/53 then 54/54 roots; CEM 55/55 then 57/57 roots); no statistical difference between groups at…
1 study · 118 participants
GRADE not reported
Plaque · Medically healthy individuals (adults and children, 6-60 years)
Salvadora persica was less effective than 0.2% chlorhexidine at reducing plaque (favours chlorhexidine); not GRADE-rated.
1 finding from 1 review
Lactobacillus count (CFU/mL) · Medically healthy individuals (adults and children, 6-60 years)
Salvadora persica rinse reduced Lactobacillus counts more than placebo (favours Salvadora persica); not GRADE-rated.
1 finding from 1 review
Dental caries · Children aged 5-7 years (early school-age)
In early school-age children (5-7 y) from heavily contaminated areas, individual studies gave conflicting DMFT/dmft differences (some favouring exposed, some non-exposed); the review did not pool them (ungraded).
4 findings from 1 review
A systematic review of the caries prevalence among children living in Chernobyl fallout countries. 2019 All outcomesChernobyl fallout areas, Eastern Europe (Ukraine, Belarus, Russian Federation) · heavy contamination
WMD -0.81 [-1.06, -0.56]
1 study · 80 participants
GRADE not reported
A systematic review of the caries prevalence among children living in Chernobyl fallout countries. 2019 All outcomesChernobyl fallout areas, Eastern Europe (Ukraine, Belarus, Russian Federation) · heavy contamination
WMD -1.03 [-1.36, -0.70]
1 study · 78 participants
GRADE not reported
A systematic review of the caries prevalence among children living in Chernobyl fallout countries. 2019 All outcomesChernobyl fallout areas, Eastern Europe (Ukraine, Belarus, Russian Federation) · heavy contamination
WMD 1.75 [1.73, 1.77]
1 study · 1474 participants
GRADE not reported
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Streptococcus mutans count · Medically healthy individuals (adults and children, 6-60 years)
Salvadora persica rinse reduced Streptococcus mutans counts relative to baseline; not GRADE-rated.
1 finding from 1 review
Arrest or reversal of noncavitated approximal carious lesions · Children and adults with noncavitated carious lesions on approximal surfaces (primary and permanent teeth)
5% NaF varnish may not differ from Resin infiltration + 5% NaF varnish for arrest or reversal of approximal carious lesions (RR 0.5, 95% CI 0.18 to 1.37; very low certainty).
1 finding from 1 review
Restorative index (RI), permanent teeth · Children aged 1-18 years
The restorative index for permanent teeth could not be meta-analyzed (no variance data); it was lower or equal in children with learning disabilities in 4 of 9 studies, and the pattern suggested more extraction- than restoration-based care in CLD (certainty not graded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
A single RCT found higher pulpotomy success with triple antibiotic paste than abscess remedy (100% vs 80%; statistically significant, P<0.05; not pooled; ungraded).
1 finding from 1 review
Single RCT (Eppa 2018, 3-arm; 20 TAP and 20 AR teeth): TAP 100% (20/20) vs abscess remedy 80% (16/20) clinical and radiographic success; difference statistically significant at 3, 6, 9, 12, 18 and 24 months (P<0.05);…
1 study · 40 participants
GRADE not reported
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
38% SDF solution (applied annually) may not differ from 5,000-ppm F (1.1% NaF) toothpaste or gel for arrest or reversal of root carious lesions (RR 0.72, 95% CI 0.18 to 2.95; very low certainty).
1 finding from 1 review
Pathological periapical radiolucency · Children with carious vital pulp exposure in primary incisors
Two trials reported periapical radiolucency but results were not pooled owing to considerable heterogeneity.
1 finding from 1 review
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
5% NaF varnish may not differ from 5,000-ppm F (1.1% NaF) toothpaste or gel for arrest or reversal of root carious lesions (RR 1.13, 95% CI 0.1 to 13.12; very low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated approximal carious lesions · Children and adults with noncavitated carious lesions on approximal surfaces (primary and permanent teeth)
5% NaF varnish may not differ from Sealant for arrest or reversal of approximal carious lesions (RR 0.95, 95% CI 0.38 to 2.41; very low certainty).
1 finding from 1 review