Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,645 questions in 107 reviews · Wounds

current versions
No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Suprasorb CNP system vs the ABThera system
Adverse events (fistulae formation) · adults with an open abdomen after surgery who have not experienced trauma
Negative pressure wound therapy for managing the open abdomen in non‐trauma patients (2022) · Cochrane
RR 0.11 [0.01, 1.92]1 study · 34 participantsVery low
Suprasorb CNP system vs the ABThera system
All‐cause mortality · adults with an open abdomen after surgery who have not experienced trauma
Negative pressure wound therapy for managing the open abdomen in non‐trauma patients (2022) · Cochrane
RR 0.33 [0.04, 2.89]1 study · 34 participantsVery low
Clipping vs no hair removal
Surgical site infection (SSIs) · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
RR 0.95 [0.65, 1.39]3 studies · 1733 participantsLow
Depilatory cream vs no hair removal
Wound complications · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
no estimate extractedNRNo studies
Depilatory cream vs no hair removal
Length of stay · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
no estimate extractedNRNo studies
Depilatory cream vs no hair removal
Cost · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
no estimate extracted1 study · 267 participantsVery low
Shaving vs clipping
Surgical site infection (SSI) · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
RR 1.64 [1.16, 2.33]7 studies · 3723 participantsModerate
Shaving vs clipping
Wound complications · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
RR 1.74 [1.12, 2.71]3 studies · 1333 participantsModerate
Shaving vs clipping
Length of stay · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
no estimate extractedNRNo studies
Shaving vs clipping
Cost · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
no estimate extractedNRNo studies
Shaving vs cream
Surgical site infection (SSI) · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
RR 2.28 [1.12, 4.65]9 studies · 1593 participantsModerate
Shaving vs cream
Wound complications · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
RR 6.95 [3.45, 13.98]5 studies · 937 participantsLow
Shaving vs cream
Length of stay · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
no estimate extractedNRNo studies
Clipping vs no hair removal
Wound complications · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
no estimate extractedNRNo studies
Shaving vs cream
Cost · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
no estimate extracted3 studies · 402 participantsVery low
Hair removal the day before surgery vs hair removal on the day of surgery
Surgical site infection (SSIs) · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
RR 0.83 [0.54, 1.3]1 study · 977 participantsLow
Hair removal the day before surgery vs hair removal on the day of surgery
Wound complications · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
no estimate extractedNRNo studies
Hair removal the day before surgery vs hair removal on the day of surgery
Length of stay · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
no estimate extractedNRNo studies
Hair removal the day before surgery vs hair removal on the day of surgery
Cost · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
no estimate extractedNRNo studies
Clipping vs no hair removal
Length of stay · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
no estimate extractedNRNo studies
Clipping vs no hair removal
Cost of care · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
no estimate extractedNRNo studies
Shaving vs no hair removal
Surgical site infection (SSIs) · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
RR 1.82 [1.05, 3.14]7 studies · 1706 participantsModerate
Shaving vs no hair removal
Wound complications · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
RR 1 [0.21, 4.66]1 study · 80 participantsLow
Shaving vs no hair removal
Length of stay · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
no estimate extracted1 study · 136 participantsLow
Shaving vs no hair removal
Cost · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
no estimate extracted1 study · 278 participantsVery low
Depilatory cream vs no hair removal
Surgical site infection (SSI) · people undergoing surgery
Preoperative hair removal to reduce surgical site infection (2021) · Cochrane
RR 1.02 [0.45, 2.31]1 study · 267 participantsLow
Polyhexamethylene biguanide (PHMB) vs 0.9% saline solution
Time to healing · participants with venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
Aqueous oxygen peroxide vs sterile water
Change in ulcer size (surface area changes in cm2 from baseline) ‐ ITT ‐ after 8 weeks of · participants with venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extracted1 study · 61 participantsVery low
Aqueous oxygen peroxide vs sterile water
Procedural pain (pain measured using a 0 to 10 cm Likert scale, which gives a 0–100 pain rating (0 = no pain, 100 = very painful) ‐ ITT ‐ after 8 weeks of · participants with venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extracted1 study · 61 participantsVery low
Aqueous oxygen peroxide vs sterile water
Cost · participants with venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
Aqueous oxygen peroxide vs sterile water
Health related quality of life · participants with venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
Aqueous oxygen peroxide vs sterile water
Adverse events · participants with venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
Propyl betaine and polihexanide vs saline solution
Time to healing · participants with chronic leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
Propyl betaine and polihexanide vs saline solution
Number of wounds healed · participants with chronic leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
Propyl betaine and polihexanide vs saline solution
Change in ulcer size after 4 weeks of · participants with chronic leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extracted1 study · 38 participantsVery low
Propyl betaine and polihexanide vs saline solution
Procedural pain after 4 weeks of follow‐ up (self‐assessed, subjectively, using a validated 10‐mm visual analogue scale) · participants with chronic leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extracted1 study · 38 participantsVery low
Propyl betaine and polihexanide vs saline solution
Cost · participants with chronic leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
Polyhexamethylene biguanide (PHMB) vs 0.9% saline solution
Number of wounds healed · participants with venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
Propyl betaine and polihexanide vs saline solution
Health related quality of life · participants with chronic leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
Propyl betaine and polihexanide vs saline solution
Adverse events after 4 weeks of · participants with chronic leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extracted1 study · 38 participantsVery low
OHP vs Ringer's solution
Time to complete wound healing · participants with treating venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
OHP vs Ringer's solution
Number of wounds healed after 12 weeks of · participants with treating venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
RR 0.96 [0.53, 1.72]1 study · 99 participantsVery low
OHP vs Ringer's solution
Change in ulcer size over time (cm2) after week 12 of · participants with treating venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extracted1 study · 99 participantsVery low
OHP vs Ringer's solution
Procedural pain · participants with treating venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
OHP vs Ringer's solution
Cost · participants with treating venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
OHP vs Ringer's solution
Health related quality of life · participants with treating venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
OHP vs Ringer's solution
Adverse events after week 12 of · participants with treating venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
RR 0.58 [0.29, 1.14]1 study · 126 participantsVery low
Polyhexamethylene biguanide (PHMB) vs 0.9% saline solution
Change in ulcer size over time · participants with venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
Polyhexamethylene biguanide (PHMB) vs 0.9% saline solution
Pain · participants with venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies
Polyhexamethylene biguanide (PHMB) vs 0.9% saline solution
Cost · participants with venous leg ulcers
Wound cleansing for treating venous leg ulcers (2021) · Cochrane
no estimate extractedNRNo studies