What do systematic reviews say?

Vitamin D plus calcium vs placebo

The review found no eligible studies for this question.

• Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Vitamin D plus calcium vs placebo

Vitamin D plus calcium showed no clear difference in adverse events: renal calculi compared with placebo (moderate certainty).

• Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
  RR 1.49 [0.7, 3.17]
  2 studies · 2931 participants
  Moderate

Vitamin D plus calcium vs placebo

Vitamin D plus calcium showed no clear difference in adverse events: serum calcium above normal compared with placebo (low certainty).

• Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
  RR 2.98 [0.6, 14.74]
  1 study · 2197 participants
  Low

Vitamin D plus calcium vs placebo

Vitamin D plus calcium showed no clear difference in incidence: all cancers compared with placebo (low certainty).

• Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
  RR 0.73 [0.48, 1.11]
  3 studies · 37061 participants
  Low

Vitamin D plus calcium vs placebo

Vitamin D plus calcium showed no clear difference in mortality: all cancers compared with placebo (moderate certainty).

• Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
  RR 0.91 [0.78, 1.05]
  1 study · 34670 participants
  Moderate

Vitamin D plus calcium vs placebo

The review found no eligible studies for this question.

• Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Steroid plus vitamin D vs steroids

Steroid plus vitamin D leads to higher number of participants achieving 'response' by PGA compared with steroid (high certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 1.13 [1.06, 1.2]
  2 studies · 2226 participants
  High

Steroid plus vitamin D vs steroids

Steroid plus vitamin D probably leads to higher number of participants achieving 'clearance' by IGA compared with steroid (moderate certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 1.22 [1.08, 1.36]
  4 studies · 2474 participants
  Moderate

Steroid plus vitamin D vs steroids

Steroid plus vitamin D probably leads to higher number of participants achieving 'response' by IGA compared with steroid (moderate certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 1.15 [1.06, 1.25]
  3 studies · 2444 participants
  Moderate

Steroid plus vitamin D vs steroids

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Steroid plus vitamin D vs steroids

Steroid plus vitamin D showed no clear difference in number of participants withdrawing due to adverse events (AE) compared with steroid (moderate certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 0.88 [0.42, 1.88]
  3 studies · 2433 participants
  Moderate

Vitamin D vs placebo/no treatment

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 12 participants
  Low

Vitamin D vs placebo/no treatment

Vitamin D preparations may leads to lower number without 30% fall in PTH on two occasions compared with placebo/no treatment (low certainty).

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  RR 0.6 [0.4, 0.89]
  2 studies · 76 participants
  Low

Vitamin D vs placebo/no treatment

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 103 participants
  Low

Vitamin D vs placebo/no treatment

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 76 participants
  Moderate

Vitamin E + vitamin C vs placebo

Vitamin C and vitamin E showed no clear difference in any adverse effects of vitamin supplementation sufficient to stop… compared with placebo (moderate certainty).

• Vitamin supplementation for preventing miscarriage 2016 · Cochrane Headline outcomes only
  RR 1.16 [0.39, 3.41]
  1 study · 739 participants
  Moderate

Vitamin A vs placebo or usual care

Vitamin A supplementation probably leads to lower vitamin A deficiency compared with placebo or usual care (moderate certainty).

• Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age 2022 · Cochrane Headline outcomes only
  RR 0.71 [0.65, 0.78]
  4 studies · 2262 participants
  Moderate

Topical vitamin D derivative vs placebo

The review found no eligible studies for this question.

• Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical vitamin D derivative vs placebo

The review found no eligible studies for this question.

• Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical vitamin D derivative vs placebo

The review found no eligible studies for this question.

• Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found