Recurrent seizure at 18 months · children with febrile seizures
Intermittent rectal diclofenac showed no clear difference in recurrent seizure at 18 months compared with placebo, followed by oral ibuprofen, paracetamol, or placebo after 8… (high certainty).
1 finding from 1 review
Recurrent seizure at 24 months · children with febrile seizures
Intermittent rectal diclofenac showed no clear difference in recurrent seizure at 24 months compared with placebo, followed by oral ibuprofen, paracetamol, or placebo after 8… (high certainty).
1 finding from 1 review
Recurrent seizure at 36 months · children with febrile seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Recurrent seizure at 48 months · children with febrile seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Recurrent seizure at 60 months or greater · children with febrile seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Need for additional analgesia (4 hours after administration) · women with perineal pain in the early postpartum period
It is very uncertain whether NSAID (single administration, any dose) changes need for additional analgesia (4 hours after administration) compared with paracetamol (very low certainty).
1 finding from 1 review
Need for additional analgesia (6 hours after administration) · women with perineal pain in the early postpartum period
NSAID (single administration, any dose) may leads to lower need for additional analgesia (6 hours after administration) compared with paracetamol (low certainty).
1 finding from 1 review
Maternal drug adverse effects number of women experiencing adverse effects · women with perineal pain in the early postpartum period
1 finding from 1 review
Maternal drug adverse effects (6 hours after administration) · women with perineal pain in the early postpartum period
It is very uncertain whether NSAID (single administration, any dose) changes maternal drug adverse effects (6 hours after administration) compared with paracetamol (very low certainty).
1 finding from 1 review
Neonatal drug adverse effects ‐ not reported · women with perineal pain in the early postpartum period
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Relief of pain · women with perineal pain in the early postpartum period
NSAID (single administration, any dose) may leads to higher adequate pain relief (4 hours after administration) compared with paracetamol (low certainty).
2 findings from 1 review
Reduction in pain intensity · people with acute soft tissue injury, such as ankle sprain
1 finding from 1 review
Little or no pain at < 24 hours · people with acute soft tissue injury, such as ankle sprain
1 finding from 1 review
Little or no pain at 1 to 3 days · people with acute soft tissue injury, such as ankle sprain
It is very uncertain whether NSAID changes little or no pain at 1 to 3 days compared with combination (paracetamol and opioid) analgesic (very low certainty).
2 findings from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people with acute soft tissue injury, such as ankle sprain
1 finding from 1 review
Swelling (7th day) · people with acute soft tissue injury, such as ankle sprain
1 finding from 1 review
Return to function on day 7 or later Assessed as 'cure' · people with acute soft tissue injury, such as ankle sprain
It is very uncertain whether NSAID changes return to function on day 7 or later Assessed as 'cure' compared with combination (paracetamol and opioid) analgesic (very low certainty).
1 finding from 1 review
Gastrointestinal adverse events · people with acute soft tissue injury, such as ankle sprain
It is very uncertain whether NSAID changes gastrointestinal adverse events compared with combination (paracetamol and opioid) analgesic (very low certainty).
1 finding from 1 review
Neurological adverse effects · people with acute soft tissue injury, such as ankle sprain
It is very uncertain whether NSAID changes neurological adverse events compared with combination (paracetamol and opioid) analgesic (very low certainty).
1 finding from 1 review
Early re‐injury (with 3 months) · people with acute soft tissue injury, such as ankle sprain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found